Synthesis, characterization, and biological properties of Cr (III), Mn (II), Co (II), Ni (II), Cu (II), and Zn (II) complexes derived from 1, 3-Oxazol-5-(4H)-One
Other Title(s)
تحضير و تشخيص و الخصائص البايولوجية لمعقدات Cu (II) و Ni (II) و Co (II) و Mn (II) و Cr (III) Zn (II) المشتقة من 1، 3 -اوكسازول-5- (4H)- أون
Joint Authors
al-Husayni, Riham Abd al-Mahdi
Maryush, Asma Abd al-Baqi
Husayn, Abd al-Rasul Ali
Muhammad, Sinan Midhat
Rashid, Inam Majid
Source
Issue
Vol. 57, Issue 3A (30 Sep. 2016), pp.1629-1638, 10 p.
Publisher
University of Baghdad College of Science
Publication Date
2016-09-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract EN
New 1,3-oxazol-5(4H)-one(3) was synthesized by cyclization of[(4-Methyl phenyl-carbonyl)amino]acetic acid (2).
The starting materials were readily obtained by acylation of 2-amino acetic acid (Glycine) with 4-methyl phenyl chloride .Imidazole(4) was synthesized by reaction of compound (3) with hydrazine hydrate (99%).
Compound (4) was isolated and characterized by 1HNMR , FTIR , uv-vis spectroscopy and elemental analysis (C.H.N).
Compound (4) has been used as a ligand (L) to prepare a number of metal complexes with Cr(III), Mn(II), Co(II), Ni(II) , Cu(II) and Zn(II).
The prepared complexes were isolated and characterized by FTIR and Uv-vis spectroscopy elemental analysis (C.H.N), flame atomic absorption technique, as well as magnetic susceptibility and conductivity measurements.
The biological activity of the synthesized ligand (L) and its metal complexes were screened against the bacteria (S.
aureus, B.Subtilis) and fungi (C.albicans) at the minimum inhibitory concentration method.
Amoxiciline drug was used for comparison under similar conditions.
They showed remarkable biological activity.
American Psychological Association (APA)
al-Husayni, Riham Abd al-Mahdi& Muhammad, Sinan Midhat& Rashid, Inam Majid& Maryush, Asma Abd al-Baqi& Husayn, Abd al-Rasul Ali. 2016. Synthesis, characterization, and biological properties of Cr (III), Mn (II), Co (II), Ni (II), Cu (II), and Zn (II) complexes derived from 1, 3-Oxazol-5-(4H)-One. Iraqi Journal of Science،Vol. 57, no. 3A, pp.1629-1638.
https://search.emarefa.net/detail/BIM-701962
Modern Language Association (MLA)
al-Husayni, Riham Abd al-Mahdi…[et al.]. Synthesis, characterization, and biological properties of Cr (III), Mn (II), Co (II), Ni (II), Cu (II), and Zn (II) complexes derived from 1, 3-Oxazol-5-(4H)-One. Iraqi Journal of Science Vol. 57, no. 3A (2016), pp.1629-1638.
https://search.emarefa.net/detail/BIM-701962
American Medical Association (AMA)
al-Husayni, Riham Abd al-Mahdi& Muhammad, Sinan Midhat& Rashid, Inam Majid& Maryush, Asma Abd al-Baqi& Husayn, Abd al-Rasul Ali. Synthesis, characterization, and biological properties of Cr (III), Mn (II), Co (II), Ni (II), Cu (II), and Zn (II) complexes derived from 1, 3-Oxazol-5-(4H)-One. Iraqi Journal of Science. 2016. Vol. 57, no. 3A, pp.1629-1638.
https://search.emarefa.net/detail/BIM-701962
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1637-1638
Record ID
BIM-701962