Biochemical study on anti thyroid peroxidase in type 2 diabetic patients with thyroid disorders
Other Title(s)
دراسة كيموحيوية لإنزيم (Anti-thyroid peroxidase) في مرضى السكري النوع الثاني المصابين باعتلال الدرقية
Joint Authors
Rasin, Tawfiq Fakhir
Kazim, Riyam Abbas
al-Araji, Sanad Baqir
Source
Issue
Vol. 13, Issue 4 (31 Dec. 2016), pp.753-761, 9 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Topics
Abstract EN
Type 2 diabetes mellitus (T2DM) is the most frequent endocrinal disease commonly associated with thyroid disorders .The study is conducted at the Specialized Center for Endocrinology and Diabetes in Baghdad ,during December 2014 up to October 2015.This study was done to investigate the prevalence of anti- thyroid peroxidase (Anti-TPO) antibody in patients suffered from type 2 diabetes with thyroid disorders .The study groups included a total number of 80 subjects consisting of 60 type 2 diabetic patients divided into 20 hyperthyroidism subjects (group 1) ,20 hypothyroidism subjects (group 2), 20 euthyroidism subjects (group 3) and 20 healthy controls (group 4) .
The fasting blood samples were analyzed for (T3,T4,TSH) by using Vitek Immuno diagnstic Assay System (VIDAS).
Enzyme Linked Immunosorbent Assay (ELISA) is used to detect anti-thyroid peroxidase (Anti-TPO) antibody .The results show that age, gender and BMI (body mass index) have significantly higher levels in the patients groups as compared to the healthy group at (p<0.01).Among 60 type 2 diabetic patients , the hypothyroidism group showed a highest mean value (333.57 ± 104.77) of anti-TPO when compared to other groups.
The levels of T3 and T4 were significantly higher in hyperthyroidism group ,while the level of TSH was significantly higher in hypothyroidism group.
American Psychological Association (APA)
al-Araji, Sanad Baqir& Rasin, Tawfiq Fakhir& Kazim, Riyam Abbas. 2016. Biochemical study on anti thyroid peroxidase in type 2 diabetic patients with thyroid disorders. Baghdad Science Journal،Vol. 13, no. 4, pp.753-761.
https://search.emarefa.net/detail/BIM-734330
Modern Language Association (MLA)
al-Araji, Sanad Baqir…[et al.]. Biochemical study on anti thyroid peroxidase in type 2 diabetic patients with thyroid disorders. Baghdad Science Journal Vol. 13, no. 4 (2016), pp.753-761.
https://search.emarefa.net/detail/BIM-734330
American Medical Association (AMA)
al-Araji, Sanad Baqir& Rasin, Tawfiq Fakhir& Kazim, Riyam Abbas. Biochemical study on anti thyroid peroxidase in type 2 diabetic patients with thyroid disorders. Baghdad Science Journal. 2016. Vol. 13, no. 4, pp.753-761.
https://search.emarefa.net/detail/BIM-734330
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 758-760
Record ID
BIM-734330