Synthesis and characterization of new 2-quinolone sulfonamide derivatives
Other Title(s)
تحضير و تشخيص مشتقات جديدة من-2 كوينولون سلفونأمايد
Joint Authors
Ahmad, Lama Sami
Khalil, Muhammad Rifat Ahmad
al-Bayati, Rida Ibrahim
Source
Issue
Vol. 13, Issue 4 (31 Dec. 2016), pp.806-818, 13 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Topics
Abstract EN
A series of new 2-quinolone derivatives linked to benzene sulphonyl moieties were performed by many steps: the first step involved preparation of different coumarins (A1,A2) by condensation of different substituted phenols with ethyl acetoacetate.
The compound A1 was treated with nitric acid to afford two isomers of nitrocoumarin derivatives (A3) and (A4).
The prepared compounds (A2, A3) were treated with hydrazine hydrate to synthesize different 2-quinolone compounds (A5,A6) while the coumarin treated with different amines gave compounds (A7,A8).
Then the synthesized 2-quinolone compounds (A5-A8) treated with benzene sulphonyl chloride to afford new sulfonamide derivatives (A9-A12).
The synthesized compounds were characterized by FT-IR, 1H-NMR, 13C-NMR spectra and by measurement some of their physical properties.
American Psychological Association (APA)
Khalil, Muhammad Rifat Ahmad& Ahmad, Lama Sami& al-Bayati, Rida Ibrahim. 2016. Synthesis and characterization of new 2-quinolone sulfonamide derivatives. Baghdad Science Journal،Vol. 13, no. 4, pp.806-818.
https://search.emarefa.net/detail/BIM-734654
Modern Language Association (MLA)
Khalil, Muhammad Rifat Ahmad…[et al.]. Synthesis and characterization of new 2-quinolone sulfonamide derivatives. Baghdad Science Journal Vol. 13, no. 4 (2016), pp.806-818.
https://search.emarefa.net/detail/BIM-734654
American Medical Association (AMA)
Khalil, Muhammad Rifat Ahmad& Ahmad, Lama Sami& al-Bayati, Rida Ibrahim. Synthesis and characterization of new 2-quinolone sulfonamide derivatives. Baghdad Science Journal. 2016. Vol. 13, no. 4, pp.806-818.
https://search.emarefa.net/detail/BIM-734654
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 816-817
Record ID
BIM-734654