Spectrophotometric determination of sulfamethoxazole with P-N, N-dimethyl amino benzaldehyde as condensation reactio
Other Title(s)
التقدير الطيفي للسلفاميثوكسازول مع بارا داي مثيل أمينو بنزلدهايد كتفاعل تكثيف
Joint Authors
al-Ghazzali, Ala Karim Muhammad
Dikran, Sarmad Bahjat
Darwish, Samar Ahmad
al-Haydari, Abd al-Muhsin Abd al-Hamid
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 29, Issue 2 (31 Aug. 2016), pp.185-199, 15 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2016-08-31
Country of Publication
Iraq
No. of Pages
15
Main Subjects
Topics
Abstract EN
Sulfamethoxazole (SMX) was added to P-N,N-dimethyl amino benzaldehyde (PDAB) by condensation reaction in acidic medium to form, a yellow colored dye compound which exhibits maximum absorption (λmax) at 450.5 nm.
The concentration of (SMX) was determined spectrophotometrically.
The optimum reaction conditions and other analytical parameters were evaluated.
In addition to classical univariate optimization, design of experiment method has been applied in optimization of the variables affecting the color producing reaction.
Beer’s law obeyed in the concentration range of 0.1-10 μg.mL-1 with molar absorptivity of 5.7950×104 L.mol-1.cm-1.
The limit of detection and Sandell's sensitivity value were 0.078 μg.mL-1 was 4.3706 μg.cm-2 respectivily.
The proposed method could be successfully applied to the determination of (SMX) in synthetic sample and urine
American Psychological Association (APA)
Darwish, Samar Ahmad& al-Haydari, Abd al-Muhsin Abd al-Hamid& al-Ghazzali, Ala Karim Muhammad& Dikran, Sarmad Bahjat. 2016. Spectrophotometric determination of sulfamethoxazole with P-N, N-dimethyl amino benzaldehyde as condensation reactio. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 29, no. 2, pp.185-199.
https://search.emarefa.net/detail/BIM-745927
Modern Language Association (MLA)
al-Haydari, Abd al-Muhsin Abd al-Hamid…[et al.]. Spectrophotometric determination of sulfamethoxazole with P-N, N-dimethyl amino benzaldehyde as condensation reactio. Ibn al-Haitham Journal for Pure and Applied Science Vol. 29, no. 2 (2016), pp.185-199.
https://search.emarefa.net/detail/BIM-745927
American Medical Association (AMA)
Darwish, Samar Ahmad& al-Haydari, Abd al-Muhsin Abd al-Hamid& al-Ghazzali, Ala Karim Muhammad& Dikran, Sarmad Bahjat. Spectrophotometric determination of sulfamethoxazole with P-N, N-dimethyl amino benzaldehyde as condensation reactio. Ibn al-Haitham Journal for Pure and Applied Science. 2016. Vol. 29, no. 2, pp.185-199.
https://search.emarefa.net/detail/BIM-745927
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 190-198
Record ID
BIM-745927