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Synthesis, spectroscopic and biological activity studies of Azo-Schiff base and metal complexes derived from 5-methyltryptamine
Other Title(s)
تحضير و دراسة طيفية و فعالية بيولوجية لمعقدات آزو-أسس شف-المشتقة من 5-مثيل تربتامين
Joint Authors
al-Balkhi, Abd al-Majid
al-Hamdani, Abbas Ali Salih
Falah, Ahmad
Source
Damascus University Journal for the Basic Sciences
Issue
Vol. 29, Issue 2 (31 Dec. 2013), pp.21-41, 21 p.
Publisher
Publication Date
2013-12-31
Country of Publication
Syria
No. of Pages
21
Main Subjects
Abstract EN
A novel Azo-Schiff base ligand L 2-[1.5-Dimethyl-3-[2-(5-methyl-1H-indol3-yl) - ethylimino] - 2 - phenyl - 2,3 - dihydro - 1H - pyrazol - 4 - ylazo] - 5- hydroxy -benzoic acid has been synthesized from reaction 1.5-Dimethyl-3-[2-(5- methyl- 1H - indol - 3 - yl) - ethylimino] - 2 - phenyl - 2.3 - dihydro - 1H - pyrazol - 4 - ylamine (A) with m-hydroxy benzoic acid.
Then, its Zn(II), Cd(II) and Hg(II) complexes were synthesized with the general formula [ML1Cl] where M = Zn(II), Cd(II) and Hg(II) are reported.
The ligand and its metal complexes have been characterized by elemental analysis, metal content, Chloride containing, molar conductance, FT-IR, 1H and 13C- NMR, UV-Vis spectra, magnetic susceptibility, thermal analysis, and mass spectra.
The activation thermodynamic parameters, such as ΔE * , ΔH * , ΔS * ΔG * and K are calculated from the TGA curve using Coats-Red fern method.
The all prepared complexes were assayed for antibacterial (Escherichia coli and Staphylococcus aureus) activities by disc diffusion method.
The results indicate that all tested ligand and complexes show antibacterial activity against E.
coli and S aureus, as gram negative and positive bacteria.
American Psychological Association (APA)
al-Hamdani, Abbas Ali Salih& al-Balkhi, Abd al-Majid& Falah, Ahmad. 2013. Synthesis, spectroscopic and biological activity studies of Azo-Schiff base and metal complexes derived from 5-methyltryptamine. Damascus University Journal for the Basic Sciences،Vol. 29, no. 2, pp.21-41.
https://search.emarefa.net/detail/BIM-750878
Modern Language Association (MLA)
al-Hamdani, Abbas Ali Salih…[et al.]. Synthesis, spectroscopic and biological activity studies of Azo-Schiff base and metal complexes derived from 5-methyltryptamine. Damascus University Journal for the Basic Sciences Vol. 29, no. 2 (2013), pp.21-41.
https://search.emarefa.net/detail/BIM-750878
American Medical Association (AMA)
al-Hamdani, Abbas Ali Salih& al-Balkhi, Abd al-Majid& Falah, Ahmad. Synthesis, spectroscopic and biological activity studies of Azo-Schiff base and metal complexes derived from 5-methyltryptamine. Damascus University Journal for the Basic Sciences. 2013. Vol. 29, no. 2, pp.21-41.
https://search.emarefa.net/detail/BIM-750878
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 40-41
Record ID
BIM-750878