Effect of application of fenugreek (Trigonella foenum-graecum)‎ on skin wound healing in rabbits

Abstract EN

Fenugreek has a long history of medical uses in Chinese and Kurdish medicine, the objective of this study is to determine the effectiveness of topical application of fenugreek on the wound healing in rabbits.

Twenty adult healthy local breed male rabbits weighing 1600-1800 gram were used.

Animals were divided into two equal groups, by surgical aseptic technique, two surgical skin incision at length of 3 cm in the back region were done on both side of the vertebrae, then they closed by simple interrupted pattern by silk (3/0).

Control group treated with Vaseline while in treated group the wounds were covered with 10% fenugreek ointment twice daily for 21 days.

The clinical and histopathological evaluation revealed that fenugreek promote the wound healing by early formation of cellular fibrous connective tissue, granulation tissue and early maturation of fibrous connective tissues, which characterized by regular and complete layer of epidermis, when compared with control group, in conclusion this study indicated that the fenugreek was enhanced wound healing and that may be due to it is therapeutic and nutritional activities.