Relationship between serum leptin concentration and insulin resistance syndrome in patients with type 2 diabetes mellitus
Joint Authors
Shibl, Tamir H.
Azim, Nur al-Din Abd A.
Yunus, Husni A.
Sulayman, Ahmad M.
Ashmawi, Ahmad M.
Ali, Muhammad M. Nusayr
Source
Journal of Current Medical Research and Practice
Issue
Vol. 2, Issue 2 (31 Aug. 2017), pp.125-132, 8 p.
Publisher
Assiut University Faculty of Medicine
Publication Date
2017-08-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction Type 2 diabetes mellitus is known for its morbidity and mortality worldwide.
It has been demonstrated in recent studies that abnormal levels of adipocytokines may contribute to insulin resistance and type 2 diabetes.
Objective The aim of the present study was to assess the relationship between serum leptin levels and insulin resistance syndrome in type 2 diabetic patients.
Patients and methods A total of 80 individuals were enrolled into this study, and were divided into two groups –20 healthy persons comprised the control group and 60 patients with type 2 diabetes mellitus comprised the disease group.
The disease group was further divided into those with evidence of metabolic syndrome (30 patients) and those without (30 patients).
Parameters such as age, sex, and anthropometric measures and biochemical indicators such as fasting and postprandial blood sugar, HbA1c, lipid profile, leptin, and fasting insulin were determined.
Results Higher leptin and insulin levels were observed in patients with metabolic syndrome (P < 0.001).
Conclusion High serum leptin is a good indicator and can act as a minimally invasive marker for early detection of insulin resistance syndrome.
American Psychological Association (APA)
Shibl, Tamir H.& Azim, Nur al-Din Abd A.& Yunus, Husni A.& Sulayman, Ahmad M.& Ashmawi, Ahmad M.& Ali, Muhammad M. Nusayr. 2017. Relationship between serum leptin concentration and insulin resistance syndrome in patients with type 2 diabetes mellitus. Journal of Current Medical Research and Practice،Vol. 2, no. 2, pp.125-132.
https://search.emarefa.net/detail/BIM-788335
Modern Language Association (MLA)
Shibl, Tamir H.…[et al.]. Relationship between serum leptin concentration and insulin resistance syndrome in patients with type 2 diabetes mellitus. Journal of Current Medical Research and Practice Vol. 2, no. 2 (May. / Aug. 2017), pp.125-132.
https://search.emarefa.net/detail/BIM-788335
American Medical Association (AMA)
Shibl, Tamir H.& Azim, Nur al-Din Abd A.& Yunus, Husni A.& Sulayman, Ahmad M.& Ashmawi, Ahmad M.& Ali, Muhammad M. Nusayr. Relationship between serum leptin concentration and insulin resistance syndrome in patients with type 2 diabetes mellitus. Journal of Current Medical Research and Practice. 2017. Vol. 2, no. 2, pp.125-132.
https://search.emarefa.net/detail/BIM-788335
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 131-132
Record ID
BIM-788335