Detection the prevalence of adhesins and extracellular hydrolytic enzymes genes in Candida albicans biofilm formation
Other Title(s)
التحري عن سيطرة جينات الالتصاق و جينات الأنزيمات خارج خلوية في عزلات المبيضة البيضاء المكونة لغشاء الحياتي
Joint Authors
Muhammad, Najwan Abbas
Ajjah, Hamziyah Ali
al-Judi, Nimat Jamil Abd al-Baqi
Source
Issue
Vol. 58, Issue 2C (30 Jun. 2017), pp.988-1000, 13 p.
Publisher
University of Baghdad College of Science
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Abstract EN
Biofilm formation (BF) is one of the most important virulence factors of Candida spp.
The aim of this study was to detect the prevalence of genes responsible in biofilm formation of C.
albicans by conventional PCR technique.
Among 49 vaginal specimens (VC), C.
albicans was the most predominant species in percentage 22/49 (45%) and 27(55%) were non albicans.
Out of 47 oral specimens (OS), 22/47(47%) were C.
albicans, whereas 25(53%) were non albicans.
At the present study; all C.
albicans were biofilm producers with variable strength, out of 44 BF producers, 18 (40.9%) were low biofilm (LBF) with significant differences (P<0.05) between HVS and OS, 25 (56.8%) moderate or high biofilm (HBF) and just one isolate from oral was strong (very high) biofilm in percentage about 2.3% with no significant differences between HVS and OS.
Molecular study of virulence genes correlated with biofilm C.
albicans show that HWP1, ALS1, ALS3, SAP5, PLB1 and LIP8 genes were detected in 100% of C.
albicans from vaginal and oral infections.
American Psychological Association (APA)
Muhammad, Najwan Abbas& Ajjah, Hamziyah Ali& al-Judi, Nimat Jamil Abd al-Baqi. 2017. Detection the prevalence of adhesins and extracellular hydrolytic enzymes genes in Candida albicans biofilm formation. Iraqi Journal of Science،Vol. 58, no. 2C, pp.988-1000.
https://search.emarefa.net/detail/BIM-790600
Modern Language Association (MLA)
Muhammad, Najwan Abbas…[et al.]. Detection the prevalence of adhesins and extracellular hydrolytic enzymes genes in Candida albicans biofilm formation. Iraqi Journal of Science Vol. 58, no. 2C (2017), pp.988-1000.
https://search.emarefa.net/detail/BIM-790600
American Medical Association (AMA)
Muhammad, Najwan Abbas& Ajjah, Hamziyah Ali& al-Judi, Nimat Jamil Abd al-Baqi. Detection the prevalence of adhesins and extracellular hydrolytic enzymes genes in Candida albicans biofilm formation. Iraqi Journal of Science. 2017. Vol. 58, no. 2C, pp.988-1000.
https://search.emarefa.net/detail/BIM-790600
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 998-1000
Record ID
BIM-790600