In vitro anti-cancer activity of Doxycycline on some human cancer cell lines
Other Title(s)
فعالية عقار الدوكسيسيكلين على بعض الخطوط السرطانية البشرية (في الزجاج)
Joint Authors
al-Mhana, Nadiyah Matar
Zainal, Isra G.
al-Rikabi, Nahi Yusuf Yasin
Source
Iraqi Journal of Cancer and Medical Genetics
Issue
Vol. 9, Issue 2 (31 Dec. 2016), pp.162-169, 8 p.
Publisher
al-Mustansyriah University Iraqi Centre for Cancer and Medical Genetics Research
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
Doxycycline (DC) is an antibiotic that is used in the treatment of number types of infections diseases caused by bacteria and protozoa.
Doxycycline is a kind of second-generation tetracyclines which is commonly used to treat a variety of infections.
Three cancer cell lines include: human cerebral glioblastoma-multiforme (AMGM) at passages 75-84, human cervical cancer (HeLa) at 70 passages, and human pelvic rhabdomyosarcoma (RD) at 75 passages cell lines were used in this study.
The results showed that DC exerted significant cytotoxic effects with all concentrations used (50,100,150,200,250,300,350 and 400) μg/ml on all types of cell lines.
Because of cytotoxic activity, good pharmacokinetic characteristics and the safety of drug which used for many years in the treatment of infectious disease, we can conclude that these characteristics make DC a valuable treatment for many types of cancer.
American Psychological Association (APA)
al-Mhana, Nadiyah Matar& Zainal, Isra G.& al-Rikabi, Nahi Yusuf Yasin. 2016. In vitro anti-cancer activity of Doxycycline on some human cancer cell lines. Iraqi Journal of Cancer and Medical Genetics،Vol. 9, no. 2, pp.162-169.
https://search.emarefa.net/detail/BIM-818971
Modern Language Association (MLA)
al-Mhana, Nadiyah Matar…[et al.]. In vitro anti-cancer activity of Doxycycline on some human cancer cell lines. Iraqi Journal of Cancer and Medical Genetics Vol. 9, no. 2 (2016), pp.162-169.
https://search.emarefa.net/detail/BIM-818971
American Medical Association (AMA)
al-Mhana, Nadiyah Matar& Zainal, Isra G.& al-Rikabi, Nahi Yusuf Yasin. In vitro anti-cancer activity of Doxycycline on some human cancer cell lines. Iraqi Journal of Cancer and Medical Genetics. 2016. Vol. 9, no. 2, pp.162-169.
https://search.emarefa.net/detail/BIM-818971
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-818971