Study the expression of msrA,msrB and linAlinA’ genes in presence of some antibiotics in methicillin resistance staphylococcus aureus
Other Title(s)
دراسة التحري عن التعبير الجيني لجينات msrA و msrB و ‘linAlinA بوجود بعض المضادات في المكورات العنقودية المقاومة للمثيسيلين
Joint Authors
Fulayyih, Mayy Talib
Muhammad, Lama Said
Source
Issue
Vol. 59, Issue 4A (31 Dec. 2018), pp.1811-1825, 15 p.
Publisher
University of Baghdad College of Science
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
15
Main Subjects
Abstract EN
Eight isolates of methicillin resistance Staphylococcus aureus(MRSA) (SA40,SA32,SA30,SA13,SA10,SA36,SA3 and SA7) with different resistance phenotypes to macrolides , lincosamides and streptogramins Were used to detect theexpression of msrA, msrB, and linA/linA’genesby using real time polymerase chain reaction before and after treatment with antibiotics (erythromycin , clarithromycin , clindamycin and lincomycin) calibrated with triosphosphateisomerase.There highst expression of these genes was after 18 hours.
It was an induction in the expression of msrA gene in isolates (SA40,SA32,SA30 and SA13) in presence of erythromycin,however,the isolates showed reduction in expression level of this gene .
Expression of msrB gene had been estimated along with the using of clarithromycin and there was induction in msrB expression in isolates (SA40,SA30,SA32,SA13,SA36,SA10and SA7) while the expression level was reduced in isolate (SA3).
Isolates (SA03 and SA30) showed induction of linA/linA’ expression with the using of clindamycin and lincomycin respectively.
American Psychological Association (APA)
Muhammad, Lama Said& Fulayyih, Mayy Talib. 2018. Study the expression of msrA,msrB and linAlinA’ genes in presence of some antibiotics in methicillin resistance staphylococcus aureus. Iraqi Journal of Science،Vol. 59, no. 4A, pp.1811-1825.
https://search.emarefa.net/detail/BIM-852829
Modern Language Association (MLA)
Muhammad, Lama Said& Fulayyih, Mayy Talib. Study the expression of msrA,msrB and linAlinA’ genes in presence of some antibiotics in methicillin resistance staphylococcus aureus. Iraqi Journal of Science Vol. 59, no. 4A (2018), pp.1811-1825.
https://search.emarefa.net/detail/BIM-852829
American Medical Association (AMA)
Muhammad, Lama Said& Fulayyih, Mayy Talib. Study the expression of msrA,msrB and linAlinA’ genes in presence of some antibiotics in methicillin resistance staphylococcus aureus. Iraqi Journal of Science. 2018. Vol. 59, no. 4A, pp.1811-1825.
https://search.emarefa.net/detail/BIM-852829
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-852829