A comparison of oral misoprostol and intravaginal dinoprostone for induction of labour : a retrospective observational study

Joint Authors

Abu Jarad, Bakr Khidr
al-Shaykh Ali, Malak
al-Bilbisi, Muhammad
Bottcher, Bettina

Source

IUG Journal of Natural Studies

Issue

Vol. 27, Issue 2 (31 Dec. 2019), pp.42-49, 8 p.

Publisher

The Islamic University-Gaza Deanship of Research and Graduate Affairs

Publication Date

2019-12-31

Country of Publication

Palestine (Gaza Strip)

No. of Pages

8

Main Subjects

Medicine

Abstract EN

Objective: To compare the efficiency, safety and cost of 50 mcg oral Misoprostol with intravaginal Dinoprostone for labour induction in women with singleton pregnancy.

Methods: This is a retrospective study of induced deliveries using 50 mcg oral Misoprostol repeated every six hours or 3 mg vaginal Dinoprostone repeated every eight hours.

The primary outcome was delivery within 24 hours and total time from starting induction to delivery and the secondary outcomes mode of delivery as well as maternal and fetal outcomes.

Result: In total, 280 woman were included: 140 (50%) received vaginal Dinoprostone and 140 (50%) received oral Misoprostol.

Women who received Misoprostol had a lower rate of caesarean delivery (9.3% vs 18.5%, P=0.001) and lower risk of fetal distress (3.6% vs 12.8%, P=0.032).

The percentage of deliveries within 24 hours was similar in both groups.

Conclusion: Women induced with oral Misoprostol experienced less frequent failure of induction, significantly shorter duration until delivery and higher normal delivery rates than those induced with vaginal Dinoprostone.

Furthermore, oral Misoprostol was significantly less expensive when compared to vaginal Dinoprostone.

This suggests that oral Misoprostol could be a more cost effective alternative to Dinoprostone for induction of labour in low resource countries.

American Psychological Association (APA)

Abu Jarad, Bakr Khidr& al-Shaykh Ali, Malak& al-Bilbisi, Muhammad& Bottcher, Bettina. 2019. A comparison of oral misoprostol and intravaginal dinoprostone for induction of labour : a retrospective observational study. IUG Journal of Natural Studies،Vol. 27, no. 2, pp.42-49.
https://search.emarefa.net/detail/BIM-888758

Modern Language Association (MLA)

Abu Jarad, Bakr Khidr…[et al.]. A comparison of oral misoprostol and intravaginal dinoprostone for induction of labour : a retrospective observational study. IUG Journal of Natural Studies Vol. 27, no. 2 (2019), pp.42-49.
https://search.emarefa.net/detail/BIM-888758

American Medical Association (AMA)

Abu Jarad, Bakr Khidr& al-Shaykh Ali, Malak& al-Bilbisi, Muhammad& Bottcher, Bettina. A comparison of oral misoprostol and intravaginal dinoprostone for induction of labour : a retrospective observational study. IUG Journal of Natural Studies. 2019. Vol. 27, no. 2, pp.42-49.
https://search.emarefa.net/detail/BIM-888758

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 48-49

Record ID

BIM-888758