Evaluation of synergistic effect of nicotinic acid with imipenem as antibiofilm for clinical pseudomonas Aeruginosa isolates
Other Title(s)
تقييم التأثير التأزري لحامض النيكوتين مع Imipenem كمضاد للغشاء الحيوي لعزلات الزوائف الزنجارية السريرية
Joint Authors
Mahmud, Suhad Sad
Fayyd, Sarah Ali
Majid, Majid Rashid
Source
Issue
Vol. 60, Issue 1 (31 Mar. 2019), pp.50-56, 7 p.
Publisher
University of Baghdad College of Science
Publication Date
2019-03-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
The present study aims to evaluate the synergistic activity of nicotinic acid (NIC) with the Imipenem (IMI) as an anti-biofilm for clinical isolated Pseudomonas aeruginosa.
The values of minimum inhibitor concentration (MICs) for IMI and NIC (Separately) against P.
aeruginosa were (16) ug/mL and (8) ug/ml respectively.
Whereas, the concentration of NIC with IMI (as combined) for biofilm inhibition was 1 ug/ml for NIC and 4 ug/ml for IMI.
The combining of NIC with IMI showed synergistic efficacy against formation of bacterial biofilm (at MIC levels).
These results provide a conclusion that NIC combined with IMI is can be considered as a successful prospective treatment against the biofilm produced by P.
aeruginosa and as antibacterial medication
American Psychological Association (APA)
Fayyd, Sarah Ali& Majid, Majid Rashid& Mahmud, Suhad Sad. 2019. Evaluation of synergistic effect of nicotinic acid with imipenem as antibiofilm for clinical pseudomonas Aeruginosa isolates. Iraqi Journal of Science،Vol. 60, no. 1, pp.50-56.
https://search.emarefa.net/detail/BIM-892036
Modern Language Association (MLA)
Fayyd, Sarah Ali…[et al.]. Evaluation of synergistic effect of nicotinic acid with imipenem as antibiofilm for clinical pseudomonas Aeruginosa isolates. Iraqi Journal of Science Vol. 60, no. 1 (2019), pp.50-56.
https://search.emarefa.net/detail/BIM-892036
American Medical Association (AMA)
Fayyd, Sarah Ali& Majid, Majid Rashid& Mahmud, Suhad Sad. Evaluation of synergistic effect of nicotinic acid with imipenem as antibiofilm for clinical pseudomonas Aeruginosa isolates. Iraqi Journal of Science. 2019. Vol. 60, no. 1, pp.50-56.
https://search.emarefa.net/detail/BIM-892036
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 56
Record ID
BIM-892036