Ischemic changes in hypertensive patients with left ventricular Hypertrophy

Abstract EN

This study aimed to Evaluate forty five hypertensive patients with left ventricular hypertrophy were included for enrollment in a clinical research was conducted in the Al-Ryada hospital and Aden international German hospital in Aden governorate with informed consent was obtained from each participant, where analyzed in a cross-sectional manner to compare the characteristics of those with left ventricular hypertrophy and ischemia evoked on a hand grip and treadmills exercise test, in patients with no previous ischemic attacks.

Group I, n=8, versus those with a normal exercise stress tests group II, n=37.

There were no differences in age, sex, severity, and duration of hypertension between the two groups, but group I patients forty five hypertensive patients with left ventricular hypertrophy were included for enrollment in a clinical research was conducted in the Al-Ryada hospital and Aden international German hospital in Aden governorate with informed consent was obtained from each participant, where analyzed in a cross-sectional manner to compare the characteristics of those with left ventricular hypertrophy and ischemia evoked on a hand grip and treadmills exercise test, in patients with no previous ischemic attacks.

Group I, n=8, versus those with a normal exercise stress tests group II, n=37.

There were no differences in age, sex, severity, and duration of hypertension between the two groups, but group I patients were significantly more overweight.

Blood pressure at peak treadmills exercise was higher in group I despite shorter exercise duration, although resting pressures were similar.

Group I patients had evidence of more pronounced cardiac enlargement and left ventricular hypertrophy by both electrocardiograph and echocardiograph criteria (LVM P < 0.001 and ischemic changes respectively <0.001), but both groups had equally good systolic function and similar degrees of mild diastolic dysfunction.

Analysis of electrocardiograph showed a significantly greater propensity to increase heart rates in group I.

This study provide a conclusion that, hypertensive patients with LVH, overweight and attained higher systolic pressure at treadmills exercise, despite a shorter duration, have propensity for higher risk of ischemic attacks at stress.

Further study and assessment is needed in such risk patients.