Chemokines and their association with body mass index among healthy Saudis
Joint Authors
Pushparaj, Peter N.
Harakeh, Steve
Kalamegam, Gauthaman
al-Hijin, Ahmad
al-Fadul, Sulayman M.
al-Amiri, Turki
Barnawi, Salah
al-Sadun, Hadil
Mirza, Ahmad A.
Azha, Isam
Source
Saudi Journal of Biological Sciences
Issue
Vol. 27, Issue 1 (31 Jan. 2020), pp.6-11, 6 p.
Publisher
Publication Date
2020-01-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Obesity is a chronic disorder that is associated with body mass index (BMI) of greater or equal to 30 kg/m2.
The prevalence of obesity in the Kingdom of Saudi Arabia (KSA) is increasing at an alarming rate and is expected to reach 41% in men and up to 78% in women by 2022.
Since chemokines are associated with involuntary weight loss, the objective of this study was to elucidate their association with BMI among Saudis.
A questionnaire was used to collect information about diet, health conditions, and demographics from 15 men and 16 women who participated in the study.
BMI was calculated based on clinical measurements and participants were classified according to their BMI category as: normal, underweight, overweight, or obese.
Serum samples were collected for a multiplex assay using the Human Chemokine Magnetic 30-plex panel.
The serum concentration of either the monokine induced by gamma interferon (MIG) or the CXC-motif chemokine ligand 9 (CXCL-9) was significantly increased in obese men (P = 0.0194) and women (P = 0.043) as compared to underweight men and women, respectively.
However, the serum levels of other chemokines were not significantly different among the groups.
We found that MIG levels are differentially regulated in serum, based on individuals’ BMI.
American Psychological Association (APA)
Harakeh, Steve& Pushparaj, Peter N.& Kalamegam, Gauthaman& al-Hijin, Ahmad& al-Fadul, Sulayman M.& al-Amiri, Turki…[et al.]. 2020. Chemokines and their association with body mass index among healthy Saudis. Saudi Journal of Biological Sciences،Vol. 27, no. 1, pp.6-11.
https://search.emarefa.net/detail/BIM-920432
Modern Language Association (MLA)
Harakeh, Steve…[et al.]. Chemokines and their association with body mass index among healthy Saudis. Saudi Journal of Biological Sciences Vol. 27, no. 1 (Jan. 2020), pp.6-11.
https://search.emarefa.net/detail/BIM-920432
American Medical Association (AMA)
Harakeh, Steve& Pushparaj, Peter N.& Kalamegam, Gauthaman& al-Hijin, Ahmad& al-Fadul, Sulayman M.& al-Amiri, Turki…[et al.]. Chemokines and their association with body mass index among healthy Saudis. Saudi Journal of Biological Sciences. 2020. Vol. 27, no. 1, pp.6-11.
https://search.emarefa.net/detail/BIM-920432
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 10-11
Record ID
BIM-920432