Chemokines and their association with body mass index among healthy Saudis

Joint Authors

Pushparaj, Peter N.
Harakeh, Steve
Kalamegam, Gauthaman
al-Hijin, Ahmad
al-Fadul, Sulayman M.
al-Amiri, Turki
Barnawi, Salah
al-Sadun, Hadil
Mirza, Ahmad A.
Azha, Isam

Source

Saudi Journal of Biological Sciences

Issue

Vol. 27, Issue 1 (31 Jan. 2020), pp.6-11, 6 p.

Publisher

Saudi Biological Society

Publication Date

2020-01-31

Country of Publication

Saudi Arabia

No. of Pages

6

Main Subjects

Biology

Topics

Abstract EN

Obesity is a chronic disorder that is associated with body mass index (BMI) of greater or equal to 30 kg/m2.

The prevalence of obesity in the Kingdom of Saudi Arabia (KSA) is increasing at an alarming rate and is expected to reach 41% in men and up to 78% in women by 2022.

Since chemokines are associated with involuntary weight loss, the objective of this study was to elucidate their association with BMI among Saudis.

A questionnaire was used to collect information about diet, health conditions, and demographics from 15 men and 16 women who participated in the study.

BMI was calculated based on clinical measurements and participants were classified according to their BMI category as: normal, underweight, overweight, or obese.

Serum samples were collected for a multiplex assay using the Human Chemokine Magnetic 30-plex panel.

The serum concentration of either the monokine induced by gamma interferon (MIG) or the CXC-motif chemokine ligand 9 (CXCL-9) was significantly increased in obese men (P = 0.0194) and women (P = 0.043) as compared to underweight men and women, respectively.

However, the serum levels of other chemokines were not significantly different among the groups.

We found that MIG levels are differentially regulated in serum, based on individuals’ BMI.

American Psychological Association (APA)

Harakeh, Steve& Pushparaj, Peter N.& Kalamegam, Gauthaman& al-Hijin, Ahmad& al-Fadul, Sulayman M.& al-Amiri, Turki…[et al.]. 2020. Chemokines and their association with body mass index among healthy Saudis. Saudi Journal of Biological Sciences،Vol. 27, no. 1, pp.6-11.
https://search.emarefa.net/detail/BIM-920432

Modern Language Association (MLA)

Harakeh, Steve…[et al.]. Chemokines and their association with body mass index among healthy Saudis. Saudi Journal of Biological Sciences Vol. 27, no. 1 (Jan. 2020), pp.6-11.
https://search.emarefa.net/detail/BIM-920432

American Medical Association (AMA)

Harakeh, Steve& Pushparaj, Peter N.& Kalamegam, Gauthaman& al-Hijin, Ahmad& al-Fadul, Sulayman M.& al-Amiri, Turki…[et al.]. Chemokines and their association with body mass index among healthy Saudis. Saudi Journal of Biological Sciences. 2020. Vol. 27, no. 1, pp.6-11.
https://search.emarefa.net/detail/BIM-920432

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 10-11

Record ID

BIM-920432