In silico modeling of beta-lactamase protein Acinetobacter baumannii

Joint Authors

al-Wattar, Wafaq Mahmud
Abd al-Husayn, Taif M.
Sad Din, Shuruk M. K.
Abu al-Maali, Hasan Musa

Source

Iraqi Journal of Biotechnology

Issue

Vol. 18, Issue 1 (30 Apr. 2019), pp.37-42, 6 p.

Publisher

University of Baghdad Genetic Engineering and Biotechnology for Postgraduate Studies

Publication Date

2019-04-30

Country of Publication

Iraq

No. of Pages

6

Main Subjects

Biology

Topics

Abstract EN

The most common mechanism of resistance to β-lactam antibiotics in gram-negative bacteria is the production of β-lactamases that hydrolyze the drug.

Results that have been obtained from some servers that have been used in this study were gave a poor quality and prediction.

SWISS MODEL server results gave more promising result as it had 92% query coverage.

Validated was done for the model study by using QMEAN score, Ramachandran plot and ProSA server.

3D Refine and Mod Refiner were used for model refinement.

Finally, ProSA server have been used in order to revalidate the model.

American Psychological Association (APA)

Abd al-Husayn, Taif M.& Abu al-Maali, Hasan Musa& Sad Din, Shuruk M. K.& al-Wattar, Wafaq Mahmud. 2019. In silico modeling of beta-lactamase protein Acinetobacter baumannii. Iraqi Journal of Biotechnology،Vol. 18, no. 1, pp.37-42.
https://search.emarefa.net/detail/BIM-947576

Modern Language Association (MLA)

Abd al-Husayn, Taif M.…[et al.]. In silico modeling of beta-lactamase protein Acinetobacter baumannii. Iraqi Journal of Biotechnology Vol. 18, no. 1 (Apr. 2019), pp.37-42.
https://search.emarefa.net/detail/BIM-947576

American Medical Association (AMA)

Abd al-Husayn, Taif M.& Abu al-Maali, Hasan Musa& Sad Din, Shuruk M. K.& al-Wattar, Wafaq Mahmud. In silico modeling of beta-lactamase protein Acinetobacter baumannii. Iraqi Journal of Biotechnology. 2019. Vol. 18, no. 1, pp.37-42.
https://search.emarefa.net/detail/BIM-947576

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 41-42

Record ID

BIM-947576