Detectin of vaspin RS2236242 and chemerin rs17173608 gene polymorphsims in a sample of obese Iraqi polycyctic ovary syndrome women

Other Title(s)

التحري عن تعدد الأشكال الوراثية لجين الفاسبين و الكميرين في عينة من النساء العراقيات البدينات المصابات بمتلازمة تعدد الأكياس المبيضية

Joint Authors

Umran, Mahfuzah Abbas
Jasim, Rua Adil
Hammadi, Isra Hamid

Source

The Iraqi Journal of Agricultural Science

Issue

Vol. 51, Issue 1 (29 Feb. 2020), pp.462-469, 8 p.

Publisher

University of Baghdad College of Agriculture

Publication Date

2020-02-29

Country of Publication

Iraq

No. of Pages

8

Main Topic

Biology

Topics

Abstract EN

This study was performed to detect assess Vaspin rs2236242 and Chemerin rs17173608 gene polymorphisms with its association with susceptibility of obese PCOS in Iraqi women .Blood samples from 100 women with obese PCOS and 75 healthy control women matched in age and BMI were collected from AL-Yarmouk Teaching hospital during February2018-July 2018 were enrolled in case control study. Tetra amplification refractory mutation system‐polymerase chain reaction (T-ARMS-PCR) was performed to detect the adipokine SNPs in patients and healthy women under study. Results demonstrated a significant variations in either genotype distribution and alleles frequencies between the obese PCOS and healthy women regarding vaspin rs2236242 polymorphism. The T allele increased the PCOS risk in comparison with the A allele which was the protective against PCOS, as well clear positive correlation between rs17173608 SNP of chemerin and susceptibility of PCOS was identified also, and The T allele had related with elevated PCOS risk as in comparison to the G allele. Data from this work determined for the first time a significant association between vaspin and chemerin SNPs and susceptibility PCOS risk in Iraqi obese women especially T allele .To confirm our findings new studies with large sample size and different ethnicities must be required.

American Psychological Association (APA)

Jasim, Rua Adil& Umran, Mahfuzah Abbas& Hammadi, Isra Hamid. 2020. Detectin of vaspin RS2236242 and chemerin rs17173608 gene polymorphsims in a sample of obese Iraqi polycyctic ovary syndrome women. The Iraqi Journal of Agricultural Science،Vol. 51, no. 1, pp.462-469.
https://search.emarefa.net/detail/BIM-948774

Modern Language Association (MLA)

Umran, Mahfuzah Abbas…[et al.]. Detectin of vaspin RS2236242 and chemerin rs17173608 gene polymorphsims in a sample of obese Iraqi polycyctic ovary syndrome women. The Iraqi Journal of Agricultural Science Vol. 51, no. 1 (2020), pp.462-469.
https://search.emarefa.net/detail/BIM-948774

American Medical Association (AMA)

Jasim, Rua Adil& Umran, Mahfuzah Abbas& Hammadi, Isra Hamid. Detectin of vaspin RS2236242 and chemerin rs17173608 gene polymorphsims in a sample of obese Iraqi polycyctic ovary syndrome women. The Iraqi Journal of Agricultural Science. 2020. Vol. 51, no. 1, pp.462-469.
https://search.emarefa.net/detail/BIM-948774

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 468-469

Record ID

BIM-948774