The effect of nicotine per inhalation on the diameter and epithelium thickness of the seminiferous tubules of rats

Other Title(s)

تأثير النيكوتين عن طريق الاستنشاق على قطر و سمك ظهارة النبيبات المنوية للجرذان

Joint Authors

En, Y. S.
Primarizky, H.
Widjiati, W.
Luqman, E. M.

Source

Iraqi Journal of Veterinary Sciences

Issue

Vol. 34, Issue 1 (30 Jun. 2020), pp.209-215, 7 p.

Publisher

University of Mosul College of Veterinary Medicine

Publication Date

2020-06-30

Country of Publication

Iraq

No. of Pages

7

Main Topic

Veterinary Medicine

Abstract EN

This study aimed to assess the level of testicular damage by observing the changes in the diameter and epithelium thickness of seminiferous tubules in rats that exposure to nicotine per inhalation. Thirty adult male rats were used and divided into five equal groups and treatment as follows for 20 days; Control group NaCl 0.9%, P1 nicotine 0.5 mg/kg, P2 nicotine 1.0 mg/kg, P3 nicotine 2.0 mg/kg and P4 nicotine 4.0 mg/kg. All groups were given treatment per inhalation for twenty days. At the end of treatment and the rats were sacrificed testes were collected for histopathological preparation. The testes were processed for routine paraffin embedding and staining and the sections were examined for histopathological changes. There results showed that nicotine administration induced varying degrees of structural damage to the seminiferous tubules, as the decreased in diamater and epithelium thickness of seminiferous tubules. The diameter and epithelium thickness of seminiferous tubules in four experimental groups reduced compared to the control group. This study proves that nicotine administration does decreases the spermatogenesis of rats by reducing the diameter and epithelium thickness of seminiferous tubules in testes. It also proves that the level of testicular damage is directly proportional to the dosage of nicotine administrated to male rats.

American Psychological Association (APA)

En, Y. S.& Primarizky, H.& Widjiati, W.& Luqman, E. M.. 2020. The effect of nicotine per inhalation on the diameter and epithelium thickness of the seminiferous tubules of rats. Iraqi Journal of Veterinary Sciences،Vol. 34, no. 1, pp.209-215.
https://search.emarefa.net/detail/BIM-948808

Modern Language Association (MLA)

En, Y. S.…[et al.]. The effect of nicotine per inhalation on the diameter and epithelium thickness of the seminiferous tubules of rats. Iraqi Journal of Veterinary Sciences Vol. 34, no. 1 (2020), pp.209-215.
https://search.emarefa.net/detail/BIM-948808

American Medical Association (AMA)

En, Y. S.& Primarizky, H.& Widjiati, W.& Luqman, E. M.. The effect of nicotine per inhalation on the diameter and epithelium thickness of the seminiferous tubules of rats. Iraqi Journal of Veterinary Sciences. 2020. Vol. 34, no. 1, pp.209-215.
https://search.emarefa.net/detail/BIM-948808

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 214-215

Record ID

BIM-948808