Outcomes of and challenges to management of hepatitis C virus infection
Joint Authors
al-Sharqi, Dana B.
Sanad, Sanad J.
Source
Issue
Vol. 42, Issue 2 (30 Jun. 2020), pp.110-112, 3 p.
Publisher
King Hamad University Hospital
Publication Date
2020-06-30
Country of Publication
Bahrain
No. of Pages
3
Main Subjects
Topics
Abstract EN
Background: Treatment of hepatitis C (HCV) infection is becoming more achievable due to increased accessibility to direct-acting antiviral agents (DAAs).
Objective: To evaluate the outcomes of the management of HCV-infected patients.
Success is defined as the achievement of a sustained virologic response (SVR).
Design: A Single-Center Retrospective Study.
Setting: Bahrain Defence Force Hospital, Bahrain.
Method: Sixty-six patients on DAA therapy for HCV infection were evaluated for SVR achievement, side-effects, and cirrhosis.
The characteristics of responders and non-responders to therapy were documented.
Result: Sixty-three (95.5%) patients were treated successfully with DAAs.
Three were identified as treatment failure, one due to non-compliance, and two cases had advanced cirrhosis.
Three patients reported treatment side-effects, although this did not prevent the completion of therapy.
Despite treatment, 18 (27%) patients had cirrhosis upon follow-up.
Conclusion: Most patients in Bahrain have HCV genotype 1, and the management of these patients has excellent outcomes, the vast majority achieving SVR.
A small number of treatment failures were associated with the presence of cirrhosis and non-compliance.
Further study, on a national scale, in multiple centers, is required to evaluate the extent of chronic HCV infection.
American Psychological Association (APA)
al-Sharqi, Dana B.& Sanad, Sanad J.. 2020. Outcomes of and challenges to management of hepatitis C virus infection. Bahrain Medical Bulletin،Vol. 42, no. 2, pp.110-112.
https://search.emarefa.net/detail/BIM-957992
Modern Language Association (MLA)
al-Sharqi, Dana B.& Sanad, Sanad J.. Outcomes of and challenges to management of hepatitis C virus infection. Bahrain Medical Bulletin Vol. 42, no. 2 (Jun. 2020), pp.110-112.
https://search.emarefa.net/detail/BIM-957992
American Medical Association (AMA)
al-Sharqi, Dana B.& Sanad, Sanad J.. Outcomes of and challenges to management of hepatitis C virus infection. Bahrain Medical Bulletin. 2020. Vol. 42, no. 2, pp.110-112.
https://search.emarefa.net/detail/BIM-957992
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 112
Record ID
BIM-957992