Outcomes of and challenges to management of hepatitis C virus infection

Joint Authors

al-Sharqi, Dana B.
Sanad, Sanad J.

Source

Bahrain Medical Bulletin

Issue

Vol. 42, Issue 2 (30 Jun. 2020), pp.110-112, 3 p.

Publisher

King Hamad University Hospital

Publication Date

2020-06-30

Country of Publication

Bahrain

No. of Pages

3

Main Subjects

Medicine

Topics

Abstract EN

Background: Treatment of hepatitis C (HCV) infection is becoming more achievable due to increased accessibility to direct-acting antiviral agents (DAAs).

Objective: To evaluate the outcomes of the management of HCV-infected patients.

Success is defined as the achievement of a sustained virologic response (SVR).

Design: A Single-Center Retrospective Study.

Setting: Bahrain Defence Force Hospital, Bahrain.

Method: Sixty-six patients on DAA therapy for HCV infection were evaluated for SVR achievement, side-effects, and cirrhosis.

The characteristics of responders and non-responders to therapy were documented.

Result: Sixty-three (95.5%) patients were treated successfully with DAAs.

Three were identified as treatment failure, one due to non-compliance, and two cases had advanced cirrhosis.

Three patients reported treatment side-effects, although this did not prevent the completion of therapy.

Despite treatment, 18 (27%) patients had cirrhosis upon follow-up.

Conclusion: Most patients in Bahrain have HCV genotype 1, and the management of these patients has excellent outcomes, the vast majority achieving SVR.

A small number of treatment failures were associated with the presence of cirrhosis and non-compliance.

Further study, on a national scale, in multiple centers, is required to evaluate the extent of chronic HCV infection.

American Psychological Association (APA)

al-Sharqi, Dana B.& Sanad, Sanad J.. 2020. Outcomes of and challenges to management of hepatitis C virus infection. Bahrain Medical Bulletin،Vol. 42, no. 2, pp.110-112.
https://search.emarefa.net/detail/BIM-957992

Modern Language Association (MLA)

al-Sharqi, Dana B.& Sanad, Sanad J.. Outcomes of and challenges to management of hepatitis C virus infection. Bahrain Medical Bulletin Vol. 42, no. 2 (Jun. 2020), pp.110-112.
https://search.emarefa.net/detail/BIM-957992

American Medical Association (AMA)

al-Sharqi, Dana B.& Sanad, Sanad J.. Outcomes of and challenges to management of hepatitis C virus infection. Bahrain Medical Bulletin. 2020. Vol. 42, no. 2, pp.110-112.
https://search.emarefa.net/detail/BIM-957992

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 112

Record ID

BIM-957992