The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour
Joint Authors
Sykes, Lynne
MacIntyre, David A.
Yap, Xiao J.
Teoh, Tiong Ghee
Bennett, Phillip R.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-07
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Pregnancy is a unique immunological state in which a balance of immune tolerance and suppression is needed to protect the fetus without compromising the mother.
It has long been established that a bias from the T helper 1 cytokine profile towards the T helper 2 profile contributes towards successful pregnancy maintenance.
The majority of publications that report on aberrant Th1:Th2 balance focus on early pregnancy loss and preeclampsia.
Over the last few decades, there has been an increased awareness of the role of infection and inflammation in preterm labour, and the search for new biomarkers to predict preterm labour continues.
In this paper, we explore the evidence for an aberrant Th1:Th2 profile associated with preterm labour.
We also consider the potential for its use in screening women at high risk of preterm labour and for prophylactic therapeutic measures for the prevention of preterm labour and associated neonatal adverse outcomes.
American Psychological Association (APA)
Sykes, Lynne& MacIntyre, David A.& Yap, Xiao J.& Teoh, Tiong Ghee& Bennett, Phillip R.. 2012. The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1001263
Modern Language Association (MLA)
Sykes, Lynne…[et al.]. The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour. Mediators of Inflammation No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-1001263
American Medical Association (AMA)
Sykes, Lynne& MacIntyre, David A.& Yap, Xiao J.& Teoh, Tiong Ghee& Bennett, Phillip R.. The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1001263
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1001263