Joint Involvement in Primary Sjögren’s Syndrome: An Ultrasound “Target Area Approach to Arthritis”
Joint Authors
Pineda, C.
Amezcua-Guerra, Luis M.
Hofmann, Fritz
Vargas, Angelica
Rodriguez-Henriquez, Pedro
Solano, Carla
Hernández-Díaz, Cristina
Castillo-Martinez, Diana
Ventura-Ríos, Lucio
Gutierrez, Marwin
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
To characterize the ultrasound (US) pattern of joint involvement in primary Sjögren’s syndrome (pSS).
Methods.
Seventeen patients with pSS, 18 with secondary Sjögren’s syndrome (sSS), and 17 healthy controls underwent US examinations of various articular regions.
Synovitis (synovial hypertrophy/joint effusion), power Doppler (PD) signals, and erosions were assessed.
Results.
In patients with pSS, synovitis was found in the metacarpophalangeal joints (MCP, 76%), wrists (76%), and knees (76%), while the proximal interphalangeal joints, elbows, and ankles were mostly unscathed.
Intra-articular PD signals were occasionally detected in wrists (12%), elbows (6%), and knees (6%).
Erosions were evident in the wrists of three (18%) patients with pSS, one of these also having anti-cyclic citrullinated peptide (anti-CCP) antibodies.
While US synovitis does not discriminate between sSS and pSS, demonstration of bone erosions in the 2nd MCP joints showed 28.8% sensitivity and 100% specificity for diagnosing sSS; in comparison, these figures were 72.2 and 94.1% for circulating anti-CCP antibodies.
Conclusions.
In pSS, the pattern of joint involvement by US is polyarticular, bilateral, and symmetrical.
Synovitis is the US sign most commonly found in patients with pSS, especially in MCP joints, wrists, and knees, and bone erosions also may occur.
American Psychological Association (APA)
Amezcua-Guerra, Luis M.& Hofmann, Fritz& Vargas, Angelica& Rodriguez-Henriquez, Pedro& Solano, Carla& Hernández-Díaz, Cristina…[et al.]. 2013. Joint Involvement in Primary Sjögren’s Syndrome: An Ultrasound “Target Area Approach to Arthritis”. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004790
Modern Language Association (MLA)
Amezcua-Guerra, Luis M.…[et al.]. Joint Involvement in Primary Sjögren’s Syndrome: An Ultrasound “Target Area Approach to Arthritis”. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1004790
American Medical Association (AMA)
Amezcua-Guerra, Luis M.& Hofmann, Fritz& Vargas, Angelica& Rodriguez-Henriquez, Pedro& Solano, Carla& Hernández-Díaz, Cristina…[et al.]. Joint Involvement in Primary Sjögren’s Syndrome: An Ultrasound “Target Area Approach to Arthritis”. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004790