Abnormal Cell Responses and Role of TNF-α in Impaired Diabetic Wound Healing

Joint Authors

Xu, Fanxing
Zhang, Chenying
Graves, Dana T.

Source

BioMed Research International

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-01-20

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Medicine

Abstract EN

Impaired diabetic wound healing constitutes a major health problem.

The impaired healing is caused by complex factors such as abnormal keratinocyte and fibroblast migration, proliferation, differentiation, and apoptosis, abnormal macrophage polarization, impaired recruitment of mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs), and decreased vascularization.

Diabetes-enhanced and prolonged expression of TNF-α also contributes to impaired healing.

In this paper, we discuss the abnormal cell responses in diabetic wound healing and the contribution of TNF-α.

American Psychological Association (APA)

Xu, Fanxing& Zhang, Chenying& Graves, Dana T.. 2013. Abnormal Cell Responses and Role of TNF-α in Impaired Diabetic Wound Healing. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1005043

Modern Language Association (MLA)

Xu, Fanxing…[et al.]. Abnormal Cell Responses and Role of TNF-α in Impaired Diabetic Wound Healing. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1005043

American Medical Association (AMA)

Xu, Fanxing& Zhang, Chenying& Graves, Dana T.. Abnormal Cell Responses and Role of TNF-α in Impaired Diabetic Wound Healing. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1005043

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1005043