Amylin Uncovered: A Review on the Polypeptide Responsible for Type II Diabetes
Joint Authors
Pillay, Karen
Govender, Patrick
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-31
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Amylin is primarily responsible for classifying type II diabetes as an amyloid (protein misfolding) disease as it has great potential to aggregate into toxic nanoparticles, thereby resulting in loss of pancreatic β-cells.
Although type II diabetes is on the increase each year, possibly due to bad eating habits of modern society, research on the culprit for this disease is still in its early days.
In addition, unlike the culprit for Alzheimer’s disease, amyloid β-peptide, amylin has failed to receive attention worthy of being featured in an abundance of review articles.
Thus, the aim of this paper is to shine the spotlight on amylin in an attempt to put it onto the top of researchers’ to-do list since the secondary complications of type II diabetes have far-reaching and severe consequences on public health both in developing and fully developed countries alike.
This paper will cover characteristics of the amylin aggregates, mechanisms of toxicity, and a particular focus on inhibitors of toxicity and techniques used to assess these inhibitors.
American Psychological Association (APA)
Pillay, Karen& Govender, Patrick. 2013. Amylin Uncovered: A Review on the Polypeptide Responsible for Type II Diabetes. BioMed Research International،Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-1005211
Modern Language Association (MLA)
Pillay, Karen& Govender, Patrick. Amylin Uncovered: A Review on the Polypeptide Responsible for Type II Diabetes. BioMed Research International No. 2013 (2013), pp.1-17.
https://search.emarefa.net/detail/BIM-1005211
American Medical Association (AMA)
Pillay, Karen& Govender, Patrick. Amylin Uncovered: A Review on the Polypeptide Responsible for Type II Diabetes. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-17.
https://search.emarefa.net/detail/BIM-1005211
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005211