Inclusion Phenomena between the β-Cyclodextrin Chiral Selector and Trp-D,L, and Its Use on the Assembly of Solid Membranes

Abstract EN

The application of β-cyclodextrin (β-CD) and the chiral ionic liquids formed from β-cyclodextrin mono-6-deoxy-6-(3-methylimidazolium)-β-cyclodextrin tosylate (β-CD-IL) as chiral selectors is described.

The inclusion phenomena between the β-cyclodextrin chiral selectors and D,L-tryptophan (D,L-Trp) was studied.

The inclusion compounds were prepared by grinding, and their properties analyzed by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and nuclear magnetic resonance (NMR).

The separation factor between β-CD and β-CD-IL with D,L-Trp was studied by the saturated solution method.

This indicated a different binding capacity of β-CD and β-CD-IL to the two enantiomers.

This result shows that the chiral ionic liquids have a higher separation factor because of their high solubility.

The β-cyclodextrin chiral ionic liquids and CS were cross-linked and immobilized on an N6 membrane to form composite membranes.

Adsorption experiments and permeation experiments were carried out.

105.43 mg D,L-Trp/g membrane was obtained.