Resveratrol as a Therapeutic Agent for Alzheimer’s Disease
Joint Authors
Ma, Teng
Tan, Lan
Tan, Meng-Shan
Yu, Jin-Tai
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-26
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Alzheimer’s disease (AD) is the most common cause of dementia, but there is no effective therapy till now.
The pathogenic mechanisms of AD are considerably complex, including Aβ accumulation, tau protein phosphorylation, oxidative stress, and inflammation.
Exactly, resveratrol, a polyphenol in red wine and many plants, is indicated to show the neuroprotective effect on mechanisms mostly above.
Recent years, there are numerous researches about resveratrol acting on AD in many models, both in vitro and in vivo.
However, the effects of resveratrol are limited by its pool bioavailability; therefore researchers have been trying a variety of methods to improve the efficiency.
This review summarizes the recent studies in cell cultures and animal models, mainly discusses the molecular mechanisms of the neuroprotective effects of resveratrol, and thus investigates the therapeutic potential in AD.
American Psychological Association (APA)
Ma, Teng& Tan, Meng-Shan& Yu, Jin-Tai& Tan, Lan. 2014. Resveratrol as a Therapeutic Agent for Alzheimer’s Disease. BioMed Research International،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1016242
Modern Language Association (MLA)
Ma, Teng…[et al.]. Resveratrol as a Therapeutic Agent for Alzheimer’s Disease. BioMed Research International No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1016242
American Medical Association (AMA)
Ma, Teng& Tan, Meng-Shan& Yu, Jin-Tai& Tan, Lan. Resveratrol as a Therapeutic Agent for Alzheimer’s Disease. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1016242
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016242