Hexarelin Signaling to PPARγ in Metabolic Diseases
Joint Authors
Demers, Annie
Tremblay, André
Rodrigue-Way, Amélie
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2007-11-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Investigating the metabolic functions of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) has been extremely rewarding over the past years.
Uncovering the biologic roles of PPARγ and its mechanism of action has greatly advanced our understanding of the transcriptional control of lipid and glucose metabolism, and compounds such as thiazolidinediones which directly regulate PPARγ have proven to exhibit potent insulin-sensitizer effects in the treatment of diabetes.
We review here recent advances on the emerging role of growth hormone releasing peptides in regulating PPARγ through interaction with scavenger receptor CD36 and ghrelin GHS-R1a receptor.
With the impact that these peptides exert on the metabolic pathways involved in lipid metabolism and energy homeostasis, it is hoped that the development of novel approaches in the regulation of PPAR functions will bring additional therapeutic possibilities to face problems related to metabolic diseases.
American Psychological Association (APA)
Demers, Annie& Rodrigue-Way, Amélie& Tremblay, André. 2007. Hexarelin Signaling to PPARγ in Metabolic Diseases. PPAR Research،Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-1027062
Modern Language Association (MLA)
Demers, Annie…[et al.]. Hexarelin Signaling to PPARγ in Metabolic Diseases. PPAR Research No. 2008 (2008), pp.1-9.
https://search.emarefa.net/detail/BIM-1027062
American Medical Association (AMA)
Demers, Annie& Rodrigue-Way, Amélie& Tremblay, André. Hexarelin Signaling to PPARγ in Metabolic Diseases. PPAR Research. 2007. Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-1027062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1027062