Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial
Joint Authors
Schetinger, Maria Rosa Chitolina
Santos Araújo, Maria do Carmo
Gutierres, Jessie
Dalmora, Sergio L.
Flores, Nélia
Farias, Julia
Cruz, Ivana de
Chiesa, Juarez
Morsch, Vera Maria
Farias, Iria Luiza Gomes
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Breast cancer is the most frequent neoplasm affecting women worldwide.
Some of the recommended treatments involve chemotherapy whose toxic effects include leukopenia and neutropenia.
This study assessed the effectiveness of Uncaria tomentosa (Ut) in reducing the adverse effects of chemotherapy through a randomized clinical trial.
Patients with Invasive Ductal Carcinoma—Stage II, who underwent a treatment regimen known as FAC (Fluorouracil, Doxorubicin, Cyclophosphamide), were divided into two groups: the UtCa received chemotherapy plus 300 mg dry Ut extract per day and the Ca group that only received chemotherapy and served as the control experiment.
Blood samples were collected before each one of the six chemotherapy cycles and blood counts, immunological parameters, antioxidant enzymes, and oxidative stress were analyzed.
Uncaria tomentosa reduced the neutropenia caused by chemotherapy and was also able to restore cellular DNA damage.
We concluded that Ut is an effective adjuvant treatment for breast cancer.
American Psychological Association (APA)
Santos Araújo, Maria do Carmo& Farias, Iria Luiza Gomes& Gutierres, Jessie& Dalmora, Sergio L.& Flores, Nélia& Farias, Julia…[et al.]. 2012. Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028461
Modern Language Association (MLA)
Santos Araújo, Maria do Carmo…[et al.]. Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-1028461
American Medical Association (AMA)
Santos Araújo, Maria do Carmo& Farias, Iria Luiza Gomes& Gutierres, Jessie& Dalmora, Sergio L.& Flores, Nélia& Farias, Julia…[et al.]. Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028461
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1028461
