Differentiation of Benign Angiomatous and Microcystic Meningiomas with Extensive Peritumoral Edema from High Grade Meningiomas with Aid of Diffusion Weighted MRI
Joint Authors
Azizyan, Avetis
Eboli, Paula
Mirocha, James
Maya, Marcel M.
Drazin, Doniel G.
Bannykh, Serguei I.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To determine whether angiomatous and microcystic meningiomas which mimic high grade meningiomas based on extent of peritumoral edema can be reliably differentiated as low grade tumors using normalized apparent diffusion coefficient (ADC) values.
Methods.
Preoperative magnetic resonance imaging (MRI) of seventy patients with meningiomas was reviewed.
Morphologically, the tumors were divided into 3 groups.
Group 1 contained 12 pure microcystic, 3 pure angiomatoid and 7 mixed angiomatoid and microcystic tumors.
Group 2 included World Health Organization (WHO) grade II and WHO grade III tumors, of which 28 were atypical and 9 were anaplastic meningiomas.
Group 3 included WHO grade I tumors of morphology different than angiomatoid and microcystic.
Peritumoral edema, normalized ADC, and cerebral blood volume (CBV) were obtained for all meningiomas.
Results.
Edema index of tumors in group 1 and group 2 was significantly higher than in group 3.
Normalized ADC value in group 1 was higher than in group 2, but not statistically significant between groups 1 and 3.
CBV values showed no significant group differences.
Conclusion.
A combination of peritumoral edema index and normalized ADC value is a novel approach to preoperative differentiation between true aggressive meningiomas and mimickers such as angiomatous and microcystic meningiomas.
American Psychological Association (APA)
Azizyan, Avetis& Eboli, Paula& Drazin, Doniel G.& Mirocha, James& Maya, Marcel M.& Bannykh, Serguei I.. 2014. Differentiation of Benign Angiomatous and Microcystic Meningiomas with Extensive Peritumoral Edema from High Grade Meningiomas with Aid of Diffusion Weighted MRI. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034524
Modern Language Association (MLA)
Azizyan, Avetis…[et al.]. Differentiation of Benign Angiomatous and Microcystic Meningiomas with Extensive Peritumoral Edema from High Grade Meningiomas with Aid of Diffusion Weighted MRI. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1034524
American Medical Association (AMA)
Azizyan, Avetis& Eboli, Paula& Drazin, Doniel G.& Mirocha, James& Maya, Marcel M.& Bannykh, Serguei I.. Differentiation of Benign Angiomatous and Microcystic Meningiomas with Extensive Peritumoral Edema from High Grade Meningiomas with Aid of Diffusion Weighted MRI. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034524
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1034524