Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral IschemicReperfusion Injury in Mice
Joint Authors
Sun, Ya-Xuan
Liu, Ting
Dai, Xue-Ling
Li, Ya-Bo
Li, Yu-Yao
Zhang, Hua
An, Li-Zhe
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The purpose of the present study was to clarify whether the water extract of Chorispora bungeana was an antioxidant agent against cerebral ischemia/reperfusion (I/R).
Our results showed that water extract of Chorispora bungeana treatment significantly reduced neurological deficit scores, infarct size, MDA and carbonyl contents, and GSH/GSSG ratio compared with the model control group.
After being treated by Chorispora bungeana, SOD, CAT, and GSH-Px activities remarkably increased.
Chorispora bungeana treatment also improved 8-OHdG expression and cell apoptosis.
Our findings indicated that the water extract of Chorispora bungeana possesses neuroprotective effect which is most likely achieved by antioxidant and antiapoptotic activities.
American Psychological Association (APA)
Sun, Ya-Xuan& Liu, Ting& Dai, Xue-Ling& Li, Ya-Bo& Li, Yu-Yao& Zhang, Hua…[et al.]. 2014. Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral IschemicReperfusion Injury in Mice. Journal of Chemistry،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1039967
Modern Language Association (MLA)
Sun, Ya-Xuan…[et al.]. Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral IschemicReperfusion Injury in Mice. Journal of Chemistry No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1039967
American Medical Association (AMA)
Sun, Ya-Xuan& Liu, Ting& Dai, Xue-Ling& Li, Ya-Bo& Li, Yu-Yao& Zhang, Hua…[et al.]. Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral IschemicReperfusion Injury in Mice. Journal of Chemistry. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1039967
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1039967