Role of Cellular Immunity in Cow’s Milk Allergy: Pathogenesis, Tolerance Induction, and Beyond
Joint Authors
Jo, Juandy
Garssen, Johan
Knippels, Leon
Sandalova, Elena
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Food allergy is an aberrant immune-mediated reaction against harmless food substances, such as cow’s milk proteins.
Due to its very early introduction, cow’s milk allergy is one of the earliest and most common food allergies.
For this reason cow’s milk allergy can be recognized as one of the first indications of an aberrant inflammatory response in early life.
Classically, cow’s milk allergy, as is true for most other allergies as well, is primarily associated with abnormal humoral immune responses, that is, elevation of specific immunoglobulin E levels.
There is growing evidence indicating that cellular components of both innate and adaptive immunity play significant roles during the pathogenesis of cow’s milk allergy.
This is true for the initiation of the allergic phenotype (stimulation and skewing towards sensitization), development and outgrowth of the allergic disease.
This review discusses findings pertaining to roles of cellular immunity in allergic inflammation, and tolerance induction against cow’s milk proteins.
In addition, a possible interaction between immune mechanisms underlying cow’s milk allergy and other types of inflammation (infections and noncommunicable diseases) is discussed.
American Psychological Association (APA)
Jo, Juandy& Garssen, Johan& Knippels, Leon& Sandalova, Elena. 2014. Role of Cellular Immunity in Cow’s Milk Allergy: Pathogenesis, Tolerance Induction, and Beyond. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1043403
Modern Language Association (MLA)
Jo, Juandy…[et al.]. Role of Cellular Immunity in Cow’s Milk Allergy: Pathogenesis, Tolerance Induction, and Beyond. Mediators of Inflammation No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1043403
American Medical Association (AMA)
Jo, Juandy& Garssen, Johan& Knippels, Leon& Sandalova, Elena. Role of Cellular Immunity in Cow’s Milk Allergy: Pathogenesis, Tolerance Induction, and Beyond. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1043403
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043403