Continuous Dynamic Registration of Microvascularization of Liver Tumors with Contrast-Enhanced Ultrasound
Joint Authors
Beyer, Lukas Philipp
Pregler, Benedikt
Wiesinger, Isabel
Stroszczynski, Christian
Wiggermann, Philipp
Jung, Ernst-Michael
Source
Radiology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-02
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
To evaluate the diagnostic value of quantification of liver tumor microvascularization using contrast-enhanced ultrasound (CEUS) measured continuously from the arterial phase to the late phase (3 minutes).
Material and Methods.
We present a retrospective analysis of 20 patients with malignant (n=13) or benign (n=7) liver tumors.
The tumors had histopathologically been proven or clearly identified using contrast-enhanced reference imaging with either 1.5 T MRI (liver specific contrast medium) or triphase CT and follow-up.
CEUS was performed using a multifrequency transducer (1–5 MHz) and a bolus injection of 2.4 mL sulphur hexafluoride microbubbles.
A retrospective perfusion analysis was performed to determine TTP (time-to-peak), RBV (regional blood volume), RBF (regional blood flow), and Peak.
Results.
Statistics revealed a significant difference (P<0.05) between benign and malignant tumors in the RBV, RBF, and Peak but not in TTP (P=0.07).
Receiver operating curves (ROC) were generated for RBV, RBF, Peak, and TTP with estimated ROC areas of 0.97, 0.96, 0.98, and 0.76, respectively.
Conclusion.
RBV, RBF, and Peak continuously measured over a determined time period of 3 minutes could be of valuable support in differentiating malignant from benign liver tumors.
American Psychological Association (APA)
Beyer, Lukas Philipp& Pregler, Benedikt& Wiesinger, Isabel& Stroszczynski, Christian& Wiggermann, Philipp& Jung, Ernst-Michael. 2014. Continuous Dynamic Registration of Microvascularization of Liver Tumors with Contrast-Enhanced Ultrasound. Radiology Research and Practice،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1047420
Modern Language Association (MLA)
Beyer, Lukas Philipp…[et al.]. Continuous Dynamic Registration of Microvascularization of Liver Tumors with Contrast-Enhanced Ultrasound. Radiology Research and Practice No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1047420
American Medical Association (AMA)
Beyer, Lukas Philipp& Pregler, Benedikt& Wiesinger, Isabel& Stroszczynski, Christian& Wiggermann, Philipp& Jung, Ernst-Michael. Continuous Dynamic Registration of Microvascularization of Liver Tumors with Contrast-Enhanced Ultrasound. Radiology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1047420
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047420