The Role of Disease Activity Score 28 in the Evaluation of Articular Involvement in Systemic Lupus Erythematosus
Joint Authors
Spinelli, F. R.
Valesini, Guido
Conti, Fabrizio
Ceccarelli, Fulvia
Massaro, Laura
Pacucci, Viviana Antonella
Cipriano, Enrica
Truglia, Simona
Miranda, Francesca
Alessandri, Cristiano
Perricone, Carlo
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Objectives.
To evaluate the application of Disease Activity Score 28 (DAS28) to assess joint involvement in Systemic Lupus Erythematosus (SLE).
Methods.
Sixty-nine SLE patients, complaining of joint symptoms, and 44 rheumatoid arthritis (RA) patients were enrolled.
In SLE patients disease activity was assessed with SLEDAI-2K.
DAS28 was calculated in all the patients.
Results.
Thirty SLE patients (43.5%) showed clinical signs of arthritis.
Mean DAS28 was 4.0 ± 1.4 , 22 patients (31.9%) had low disease activity, 29 (42.0%) moderate, and 18 (26.1%) high.
We dichotomized SLE patients according to the presence (Group 1) or absence (Group 2) of articular involvement according to SLEDAI-2K: 56.3% of the patients of the second group had a moderate/high activity according to DAS28.
We compared SLE patients with 44 RA patients (M/F 9/35, mean age 55.6 ± 14.5 years; mean disease duration 140.4 ± 105.6 months).
No significant differences were found regarding the values of DAS28 between SLE and RA patients.
On the contrary, the values of tender and swollen joint count were significantly higher in RA compared to SLE patients ( P = 0.0002 and P = 0.0001 , resp.).
Conclusions.
We suggest the use of the DAS28 in the assessment of joint involvement in SLE patients.
American Psychological Association (APA)
Ceccarelli, Fulvia& Perricone, Carlo& Massaro, Laura& Pacucci, Viviana Antonella& Cipriano, Enrica& Truglia, Simona…[et al.]. 2014. The Role of Disease Activity Score 28 in the Evaluation of Articular Involvement in Systemic Lupus Erythematosus. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048832
Modern Language Association (MLA)
Ceccarelli, Fulvia…[et al.]. The Role of Disease Activity Score 28 in the Evaluation of Articular Involvement in Systemic Lupus Erythematosus. The Scientific World Journal No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1048832
American Medical Association (AMA)
Ceccarelli, Fulvia& Perricone, Carlo& Massaro, Laura& Pacucci, Viviana Antonella& Cipriano, Enrica& Truglia, Simona…[et al.]. The Role of Disease Activity Score 28 in the Evaluation of Articular Involvement in Systemic Lupus Erythematosus. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1048832
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1048832