Resistance to Cotrimoxazole and Other Antimicrobials among Isolates from HIVAIDS and Non-HIVAIDS Patients at Bugando Medical Centre, Mwanza, Tanzania
Joint Authors
Marwa, Karol J.
Mushi, Martha F.
Konje, Eveline
Alele, Paul E.
Kidola, Jeremiah
Mirambo, Mariam M.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Bacterial resistance has increased in the AIDS era and is attributed to the widespread use of cotrimoxazole prophylaxis against opportunistic infections in HIV/AIDS patients.
In Tanzania, cotrimoxazole prophylaxis has been used for more than ten years.
Little is known, however, about its impact on the spread of antibiotic resistance in HIV positive patients.
This cross-sectional study was done to compare magnitude of bacterial resistance to cotrimoxazole and other antimicrobials among isolates from HIV infected patients on cotrimoxazole prophylaxis and those not on prophylaxis and non-HIV patients attending Bugando Medical Centre (BMC).
Susceptibility testing on obtained urine and swab specimens followed Clinical Laboratory Standard Institute, 2010, Guidelines.
Of 945 samples collected, 155 had positive bacterial growth after 24 hours of incubation.
Of the positive samples (72), 46.4% were from HIV positive patients.
The common isolates were E.
coli 41.3% (64/155), Klebsiella pneumoniae 17.5% (27/155), and Staphylococcus aureus 16.1% (25/155).
Overall, bacterial resistance to cotrimoxazole was 118 (76.1%); among isolates from HIV patients bacterial resistance was 54 (75%), and for isolates from HIV patients on prophylaxis bacterial resistance was 36 (81.3%).
HIV seropositivity and cotrimoxazole prophylaxis are not associated with antibiotic resistance observed in bacteria infecting patients attending BMC, Mwanza, Tanzania.
American Psychological Association (APA)
Marwa, Karol J.& Mushi, Martha F.& Konje, Eveline& Alele, Paul E.& Kidola, Jeremiah& Mirambo, Mariam M.. 2015. Resistance to Cotrimoxazole and Other Antimicrobials among Isolates from HIVAIDS and Non-HIVAIDS Patients at Bugando Medical Centre, Mwanza, Tanzania. AIDS Research and Treatment،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1053957
Modern Language Association (MLA)
Marwa, Karol J.…[et al.]. Resistance to Cotrimoxazole and Other Antimicrobials among Isolates from HIVAIDS and Non-HIVAIDS Patients at Bugando Medical Centre, Mwanza, Tanzania. AIDS Research and Treatment No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1053957
American Medical Association (AMA)
Marwa, Karol J.& Mushi, Martha F.& Konje, Eveline& Alele, Paul E.& Kidola, Jeremiah& Mirambo, Mariam M.. Resistance to Cotrimoxazole and Other Antimicrobials among Isolates from HIVAIDS and Non-HIVAIDS Patients at Bugando Medical Centre, Mwanza, Tanzania. AIDS Research and Treatment. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1053957
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1053957