Effect of Leukocyte-Rich and Platelet-Rich Plasma on Healing of a Horizontal Medial Meniscus Tear in a Rabbit Model
Joint Authors
Shin, Kyun Ho
Lee, Haseok
Kang, Seonghyun
Ko, You-Jin
Lee, Seung-Yup
Park, Jung-Ho
Bae, Ji-Hoon
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
There are limited reports on the effect of platelet-rich plasma (PRP) on meniscus healing.
The purpose of this study was to investigate the effect of leukocyte-rich PRP (L-PRP) on potential healing of the horizontal medial meniscus tears in a rabbit model.
A horizontal medial meniscus tear was created in both knees of nine skeletally mature adult rabbits.
Left or right knees were randomly assigned to a L-PRP group, or a control group.
0.5 mL of L-PRP from 10 mL of each rabbit’s whole blood was prepared and injected into the horizontal tears in a L-PRP group.
None was applied to the horizontal tears in a control group.
The histological assessment of meniscus healing was performed at two, four, and six weeks after surgery.
We found that there were no significant differences of quantitative histologic scoring between two groups at 2, 4, and 6 weeks after surgery (p>0.05).
This study failed to show the positive effect of single injection of L-PRP on enhancing healing of the horizontal medial meniscus tears in a rabbit model.
Single injection of L-PRP into horizontal meniscus tears may not effectively enhance healing of horizontal medial meniscus tears.
American Psychological Association (APA)
Shin, Kyun Ho& Lee, Haseok& Kang, Seonghyun& Ko, You-Jin& Lee, Seung-Yup& Park, Jung-Ho…[et al.]. 2015. Effect of Leukocyte-Rich and Platelet-Rich Plasma on Healing of a Horizontal Medial Meniscus Tear in a Rabbit Model. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054519
Modern Language Association (MLA)
Shin, Kyun Ho…[et al.]. Effect of Leukocyte-Rich and Platelet-Rich Plasma on Healing of a Horizontal Medial Meniscus Tear in a Rabbit Model. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1054519
American Medical Association (AMA)
Shin, Kyun Ho& Lee, Haseok& Kang, Seonghyun& Ko, You-Jin& Lee, Seung-Yup& Park, Jung-Ho…[et al.]. Effect of Leukocyte-Rich and Platelet-Rich Plasma on Healing of a Horizontal Medial Meniscus Tear in a Rabbit Model. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1054519
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1054519