Effects of Calcium Phosphate Nanocrystals on Osseointegration of Titanium Implant in Irradiated Bone
Joint Authors
Cheung, Lim Kwong
Zheng, Li Wu
Ma, Li
Kwong, Dora Lai Wan
Li, Jun Yuan
Pow, Edmond Ho Nang
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Radiotherapy may compromise the integration of implant and cause implant loss.
Implant surface modifications have the possibility of promoting cell attachment, cell growth, and bone formation which ultimately enhance the osseointegration process.
The present study aimed to investigate the effects of calcium phosphate nanocrystals on implant osseointegration in irradiated bone.
Sixteen rabbits were randomly assigned into control and nano-CaP groups, receiving implants with dual acid-etched surface or dual acid-etched surface discretely deposited of nanoscale calcium-phosphate crystals, respectively.
The left leg of all the rabbits received 15 Gy radiation, followed by implants placement one week after.
Four animals in each group were sacrificed after 4 and 12 weeks, respectively.
Implant stability quotient (ISQ), ratio of bone volume to total volume (BV/TV), bone growth rate, and bone-to-implant contact (BIC) were evaluated.
The nano-CaP group showed significantly higher ISQ (week 12, P=0.031) and bone growth rate (week 6, P=0.021; week 9, P=0.001) than that in control group.
No significant differences in BV/TV and BIC were found between two groups.
Titanium implant surface modified with CaP nanocrystals provides a potential alternative to improve bone healing around implant in irradiated bone.
American Psychological Association (APA)
Li, Jun Yuan& Pow, Edmond Ho Nang& Zheng, Li Wu& Ma, Li& Kwong, Dora Lai Wan& Cheung, Lim Kwong. 2015. Effects of Calcium Phosphate Nanocrystals on Osseointegration of Titanium Implant in Irradiated Bone. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056711
Modern Language Association (MLA)
Li, Jun Yuan…[et al.]. Effects of Calcium Phosphate Nanocrystals on Osseointegration of Titanium Implant in Irradiated Bone. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056711
American Medical Association (AMA)
Li, Jun Yuan& Pow, Edmond Ho Nang& Zheng, Li Wu& Ma, Li& Kwong, Dora Lai Wan& Cheung, Lim Kwong. Effects of Calcium Phosphate Nanocrystals on Osseointegration of Titanium Implant in Irradiated Bone. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056711
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056711