Correlation between Gastric Mucosal Morphologic Patterns and Histopathological Severity of Helicobacter pylori Associated Gastritis Using Conventional Narrow Band Imaging Gastroscopy
Joint Authors
Tongtawee, Taweesak
Kaewpitoon, Soraya
Kaewpitoon, Natthawut
Dechsukhum, Chavaboon
Loyd, Ryan A.
Matrakool, Likit
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and Aim.
Identifying specific gastric mucosal morphologic patterns useful for detecting Helicobacter pylori associated gastritis and correlation with histopathological severity.
Methods.
The endoscopists classified the C-NBI gastroscopic findings into 5 gastric mucosal morphologic patterns as follows: type 1: regular arrangement of collecting venules, type 2: cone-shaped gastric pits, type 3: rod-shaped gastric pits with prominent sulci, type 4: ground glass-like morphology, and type 5: dark brown patches with bluish margin and irregular border.
Biopsies of all of the cases were then evaluated by 5 pathologists for definitive Helicobacter pylori diagnosis.
Result.
Type 1 and type 2 patterns were statistically significant in predicting Helicobacter pylori negative status (58/60, P<0.01).
Type 3, type 4, and type 5 patterns were statistically significant in predicting Helicobacter pylori positive status (132/140, P<0.01).
Furthermore, the sensitivity, specificity, and positive and negative predictive values of type 3, 4, or 5 morphologies for predicting Helicobacter pylori positive were 94.28%, 96.66%, 98.50%, and 87.87%, respectively, correlated well with inflammation grading according to the Sydney classification (P<0.01).
Conclusion.
Our study suggests that gastric mucosal morphologic patterns in the Helicobacter pylori infected gastric mucosa can be reliably identified using C-NBI gastroscopy with good correlation with inflammation grading.
American Psychological Association (APA)
Tongtawee, Taweesak& Kaewpitoon, Soraya& Kaewpitoon, Natthawut& Dechsukhum, Chavaboon& Loyd, Ryan A.& Matrakool, Likit. 2015. Correlation between Gastric Mucosal Morphologic Patterns and Histopathological Severity of Helicobacter pylori Associated Gastritis Using Conventional Narrow Band Imaging Gastroscopy. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056804
Modern Language Association (MLA)
Tongtawee, Taweesak…[et al.]. Correlation between Gastric Mucosal Morphologic Patterns and Histopathological Severity of Helicobacter pylori Associated Gastritis Using Conventional Narrow Band Imaging Gastroscopy. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1056804
American Medical Association (AMA)
Tongtawee, Taweesak& Kaewpitoon, Soraya& Kaewpitoon, Natthawut& Dechsukhum, Chavaboon& Loyd, Ryan A.& Matrakool, Likit. Correlation between Gastric Mucosal Morphologic Patterns and Histopathological Severity of Helicobacter pylori Associated Gastritis Using Conventional Narrow Band Imaging Gastroscopy. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056804
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056804