Participation of WNT and β-Catenin in Physiological and Pathological Endometrial Changes: Association with Angiogenesis
Joint Authors
Kmieć, Zbigniew
Kiewisz, Jolanta
Wasniewski, Tomasz
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-20
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
WNT proteins are involved in embryonic development, sex determination, stem cell recruitment, angiogenesis, and cancer.
They take part in morphological changes in the endometrium during development, regulate processes of endometrial proliferation and differentiation.
This review presents current knowledge about implication of WNT proteins and β-catenin in physiological endometrial functions as well as their involvement in uterine carcinogenesis.
Influence of WNT proteins on the formation of blood vessel, taking place both under healthy and pathological conditions, is also considered.
Participation of WNT proteins, β-catenin, and inhibitors and inducers of WNT signaling in the process of endometrial angiogenesis is largely unknown.
Thus, confirmation of their local and systemic participation in the process of endometrial angiogenesis may in the long term help to establish new diagnostic and therapeutic approaches in conditions associated with the pathology of the female reproductive system.
American Psychological Association (APA)
Kiewisz, Jolanta& Wasniewski, Tomasz& Kmieć, Zbigniew. 2015. Participation of WNT and β-Catenin in Physiological and Pathological Endometrial Changes: Association with Angiogenesis. BioMed Research International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1057016
Modern Language Association (MLA)
Kiewisz, Jolanta…[et al.]. Participation of WNT and β-Catenin in Physiological and Pathological Endometrial Changes: Association with Angiogenesis. BioMed Research International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1057016
American Medical Association (AMA)
Kiewisz, Jolanta& Wasniewski, Tomasz& Kmieć, Zbigniew. Participation of WNT and β-Catenin in Physiological and Pathological Endometrial Changes: Association with Angiogenesis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1057016
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057016