Comparative Transcriptomes and EVO-DEVO Studies Depending on Next Generation Sequencing
Joint Authors
Li, Yixue
Liu, Tiancheng
Yu, Lin
Liu, Lei
Li, Hong
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
High throughput technology has prompted the progressive omics studies, including genomics and transcriptomics.
We have reviewed the improvement of comparative omic studies, which are attributed to the high throughput measurement of next generation sequencing technology.
Comparative genomics have been successfully applied to evolution analysis while comparative transcriptomics are adopted in comparison of expression profile from two subjects by differential expression or differential coexpression, which enables their application in evolutionary developmental biology (EVO-DEVO) studies.
EVO-DEVO studies focus on the evolutionary pressure affecting the morphogenesis of development and previous works have been conducted to illustrate the most conserved stages during embryonic development.
Old measurements of these studies are based on the morphological similarity from macro view and new technology enables the micro detection of similarity in molecular mechanism.
Evolutionary model of embryo development, which includes the “funnel-like” model and the “hourglass” model, has been evaluated by combination of these new comparative transcriptomic methods with prior comparative genomic information.
Although the technology has promoted the EVO-DEVO studies into a new era, technological and material limitation still exist and further investigations require more subtle study design and procedure.
American Psychological Association (APA)
Liu, Tiancheng& Yu, Lin& Liu, Lei& Li, Hong& Li, Yixue. 2015. Comparative Transcriptomes and EVO-DEVO Studies Depending on Next Generation Sequencing. Computational and Mathematical Methods in Medicine،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1058029
Modern Language Association (MLA)
Liu, Tiancheng…[et al.]. Comparative Transcriptomes and EVO-DEVO Studies Depending on Next Generation Sequencing. Computational and Mathematical Methods in Medicine No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1058029
American Medical Association (AMA)
Liu, Tiancheng& Yu, Lin& Liu, Lei& Li, Hong& Li, Yixue. Comparative Transcriptomes and EVO-DEVO Studies Depending on Next Generation Sequencing. Computational and Mathematical Methods in Medicine. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1058029
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058029