Parkinsonism and Sjögren’s Syndrome: A Fortuitous Association or a Shared Immunopathogenesis?
Joint Authors
Kchaou, Mariem
Ben Ali, Nadia
Hmida, Intissar
Fray, Saloua
Jamoussi, Hela
Jalleli, Mohamed
Echebbi, Slim
Achouri, Afef
Belal, Samir
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
The Sjögren Syndrome (SS) can include various manifestations of central nervous system impairment.
Extrapyramidal signs are known to be very rare and unusually discovered on early onset in this pathology.
Observation.
A 46-year-old woman with a history of progressive Parkinsonism for 6 years and a normal brain magnetic resonance imaging was partially improved with levodopa therapy.
The later discovery of a sicca syndrome led to performing of further investigations, which revealed the presence of anti-SSA antibodies and a sialoadenitis of grade 4 according to Chisholm’s classification on labial salivary gland biopsy.
The diagnosis of primary SS was established and the adjunction of corticotherapy has remarkably improved Parkinson’s signs without use of other immunosuppressive agents.
Conclusion.
Based on these findings, we discuss the hypothesis of either a causal link between SS and Parkinsonism or a fortuitous association of two distinct pathologies with or without a shared immunopathogenesis.
American Psychological Association (APA)
Kchaou, Mariem& Ben Ali, Nadia& Hmida, Intissar& Fray, Saloua& Jamoussi, Hela& Jalleli, Mohamed…[et al.]. 2015. Parkinsonism and Sjögren’s Syndrome: A Fortuitous Association or a Shared Immunopathogenesis?. Case Reports in Medicine،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058845
Modern Language Association (MLA)
Kchaou, Mariem…[et al.]. Parkinsonism and Sjögren’s Syndrome: A Fortuitous Association or a Shared Immunopathogenesis?. Case Reports in Medicine No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058845
American Medical Association (AMA)
Kchaou, Mariem& Ben Ali, Nadia& Hmida, Intissar& Fray, Saloua& Jamoussi, Hela& Jalleli, Mohamed…[et al.]. Parkinsonism and Sjögren’s Syndrome: A Fortuitous Association or a Shared Immunopathogenesis?. Case Reports in Medicine. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058845