Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial
Joint Authors
Sarrafzadegan, Nizal
Asgary, Sedigheh
Soltani, Rasool
Gorji, Abdollah
Siavash, Mansour
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
The plant Cornus mas L.
(cornelian cherry) is traditionally used as an antidiabetic supplement; however, there is no related clinical trial.
In this study, we evaluated the effects of the fruit extract of this plant on biomarkers of glycemic control in adult patients with type 2 diabetes.
Methods.
Sixty patients with type 2 diabetes were randomly assigned to two groups to receive either the extract or placebo capsules (2 capsules twice daily) for 6 weeks.
Each drug capsule contained 150 mg of anthocyanins.
Fasting plasma levels of glucose, insulin, HgbA 1 C , and triglyceride as well as 2-hour postprandial glucose level (2Hpp) were measured before and after the intervention and finally the mean values were compared between groups.
Results.
After 6 weeks of intervention, significant increase in insulin level (1.13 ± 1.90 versus −0.643 ± 1.82, P < 0 .
05 ) as well as decrease in HgbA 1 C (−0.24 ± 0.429 versus 0.023 ± 0.225, P < 0 .
05 ) and TG (−23.66 ± 55.40 versus 2.83 ± 15.71, P < 0 .
05 ) levels was observed in drug group compared to placebo.
Conclusion.
Daily consumption of the fruit extract of Cornus mas L.
improves glycemic control by increasing insulin level and reduces TG serum level in type 2 diabetic adult patients.
American Psychological Association (APA)
Soltani, Rasool& Gorji, Abdollah& Asgary, Sedigheh& Sarrafzadegan, Nizal& Siavash, Mansour. 2015. Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1063543
Modern Language Association (MLA)
Soltani, Rasool…[et al.]. Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1063543
American Medical Association (AMA)
Soltani, Rasool& Gorji, Abdollah& Asgary, Sedigheh& Sarrafzadegan, Nizal& Siavash, Mansour. Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1063543
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063543