Antibacterial Effects and Mode of Action of Selected Essential Oils Components against Escherichia coli and Staphylococcus aureus
Joint Authors
Lopez-Romero, Julio Cesar
González-Ríos, Humberto
Borges, Anabela
Simões, Manuel
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Bacterial resistance has been increasingly reported worldwide and is one of the major causes of failure in the treatment of infectious diseases.
Natural-based products, including plant secondary metabolites (phytochemicals), may be used to surpass or reduce this problem.
The objective of this study was to determine the antibacterial effect and mode of action of selected essential oils (EOs) components: carveol, carvone, citronellol, and citronellal, against Escherichia coli and Staphylococcus aureus.
The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were assessed for the selected EOs components.
Moreover, physicochemical bacterial surface characterization, bacterial surface charge, membrane integrity, and K+ leakage assays were carried out to investigate the antimicrobial mode of action of EOs components.
Citronellol was the most effective molecule against both pathogens, followed by citronellal, carveol, and carvone.
Changes in the hydrophobicity, surface charge, and membrane integrity with the subsequent K+ leakage from E.
coli and S.
aureus were observed after exposure to EOs.
This study demonstrates that the selected EOs have significant antimicrobial activity against the bacteria tested, acting on the cell surface and causing the disruption of the bacterial membrane.
Moreover, these molecules are interesting alternatives to conventional antimicrobials for the control of microbial infections.
American Psychological Association (APA)
Lopez-Romero, Julio Cesar& González-Ríos, Humberto& Borges, Anabela& Simões, Manuel. 2015. Antibacterial Effects and Mode of Action of Selected Essential Oils Components against Escherichia coli and Staphylococcus aureus. Evidence-Based Complementary and Alternative Medicine،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063602
Modern Language Association (MLA)
Lopez-Romero, Julio Cesar…[et al.]. Antibacterial Effects and Mode of Action of Selected Essential Oils Components against Escherichia coli and Staphylococcus aureus. Evidence-Based Complementary and Alternative Medicine No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1063602
American Medical Association (AMA)
Lopez-Romero, Julio Cesar& González-Ríos, Humberto& Borges, Anabela& Simões, Manuel. Antibacterial Effects and Mode of Action of Selected Essential Oils Components against Escherichia coli and Staphylococcus aureus. Evidence-Based Complementary and Alternative Medicine. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1063602
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1063602