The Impact of Immune System in Regulating Bone Metastasis Formation by Osteotropic Tumors
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Bone metastases are frequent and debilitating consequence for many tumors, such as breast, lung, prostate, and kidney cancer.
Many studies report the importance of the immune system in the pathogenesis of bone metastasis.
Indeed, bone and immune system are strictly linked to each other because bone regulates the hematopoietic stem cells from which all cells of the immune system derive, and many immunoregulatory cytokines influence the fate of bone cells.
Furthermore, both cytokines and factors produced by immune and bone cells promote the growth of tumor cells in bone, contributing to supporting the vicious cycle of bone metastasis.
This review summarizes the current knowledge on the interactions among bone, immune, and tumor cells aiming to provide an overview of the osteoimmunology field in bone metastasis from solid tumors.
American Psychological Association (APA)
D’Amico, Lucia& Roato, Ilaria. 2015. The Impact of Immune System in Regulating Bone Metastasis Formation by Osteotropic Tumors. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1068368
Modern Language Association (MLA)
D’Amico, Lucia& Roato, Ilaria. The Impact of Immune System in Regulating Bone Metastasis Formation by Osteotropic Tumors. Journal of Immunology Research No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1068368
American Medical Association (AMA)
D’Amico, Lucia& Roato, Ilaria. The Impact of Immune System in Regulating Bone Metastasis Formation by Osteotropic Tumors. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1068368
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068368