The Complex Role of STAT3 in Viral Infections
Author
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Signal transducer and activators of transcription-3 (STAT3) regulates diverse biological functions including cell growth, differentiation, and apoptosis.
In addition, STAT3 plays a key role in regulating host immune and inflammatory responses and in the pathogenesis of many cancers.
Several studies reported differential regulation of STAT3 in a range of viral infections.
Interestingly, STAT3 appears to direct seemingly contradictory responses and both pro- and antiviral roles of STAT3 have been described.
This review summarized the currently known functions of STAT3 in the regulation of viral replication and pathogenesis of viral infections.
Some of the key unanswered questions and the gap in our current understanding of the role of STAT3 in viral pathogenesis are discussed.
American Psychological Association (APA)
Kuchipudi, Suresh V.. 2015. The Complex Role of STAT3 in Viral Infections. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068428
Modern Language Association (MLA)
Kuchipudi, Suresh V.. The Complex Role of STAT3 in Viral Infections. Journal of Immunology Research No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1068428
American Medical Association (AMA)
Kuchipudi, Suresh V.. The Complex Role of STAT3 in Viral Infections. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068428
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068428