CD69 Is the Crucial Regulator of Intestinal Inflammation: A New Target Molecule for IBD Treatment?

Joint Authors

Radulovic, Katarina
Niess, Jan Hendrik

Source

Journal of Immunology Research

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-02-22

Country of Publication

Egypt

No. of Pages

12

Main Subjects

Biology

Abstract EN

CD69 has been identified as an early activation marker of lymphocytes.

However, recent work has indicated that CD69 plays an essential role for the regulation of inflammatory processes.

Particularly, CD69 is highly expressed by lymphocytes at mucosal sites being constantly exposed to the intestinal microflora (one of the nature’s most complex and most densely populated microbial habitats) and food antigens, while only a small number of circulating leukocytes express this molecule.

In this review we will discuss the role of CD69 in mucosal tissue and consider CD69 as a potential target for the development of novel treatments of intestinal inflammation.

American Psychological Association (APA)

Radulovic, Katarina& Niess, Jan Hendrik. 2015. CD69 Is the Crucial Regulator of Intestinal Inflammation: A New Target Molecule for IBD Treatment?. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068496

Modern Language Association (MLA)

Radulovic, Katarina& Niess, Jan Hendrik. CD69 Is the Crucial Regulator of Intestinal Inflammation: A New Target Molecule for IBD Treatment?. Journal of Immunology Research No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1068496

American Medical Association (AMA)

Radulovic, Katarina& Niess, Jan Hendrik. CD69 Is the Crucial Regulator of Intestinal Inflammation: A New Target Molecule for IBD Treatment?. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1068496

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1068496