Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-09
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Global fish production from aquaculture has rapidly grown over the past decades, and grass carp shares the largest portion.
However, hemorrhagic disease caused by grass carp reovirus (GCRV) results in tremendous loss of grass carp (Ctenopharyngodon idella) industry.
During the past years, development of molecular biology and cellular biology technologies has promoted significant advances in the understanding of the pathogen and the immune system.
Immunoprophylaxis based on stimulation of the immune system of fish has also got some achievements.
In this review, authors summarize the recent progresses in basic researches on GCRV; viral nucleic acid sensors, high-mobility group box proteins (HMGBs); pattern recognition receptors (PRRs), Toll-like receptors (TLRs) and retinoic acid inducible gene I- (RIG-I-) like receptors (RLRs); antiviral immune responses induced by PRRs-mediated signaling cascades of type I interferon (IFN-I) and IFN-stimulated genes (ISGs) activation.
The present review also notices the potential applications of molecule genetic markers.
Additionally, authors discuss the current preventive and therapeutic strategies (vaccines, RNAi, and prevention medicine) and highlight the importance of innate immunity in long term control for grass carp hemorrhagic disease.
American Psychological Association (APA)
Rao, Youliang& Su, Jianguo. 2015. Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp. Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-18.
https://search.emarefa.net/detail/BIM-1068544
Modern Language Association (MLA)
Rao, Youliang& Su, Jianguo. Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp. Journal of Immunology Research No. 2015 (2015), pp.1-18.
https://search.emarefa.net/detail/BIM-1068544
American Medical Association (AMA)
Rao, Youliang& Su, Jianguo. Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp. Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-18.
https://search.emarefa.net/detail/BIM-1068544
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1068544