Supplementation with Red Palm Oil Increases β-Carotene and Vitamin A Blood Levels in Patients with Cystic Fibrosis
Joint Authors
Nesaretnam, Kalanithi
Mall, Marcus
Sommerburg, Olaf
De Spirt, Silke
Mattern, Annett
Joachim, Cornelia
Langhans, Claus-Dieter
Siems, Werner
Stahl, Wilhelm
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Patients with cystic fibrosis (CF) show decreased plasma concentrations of antioxidants due to malabsorption of lipid soluble vitamins and consumption by chronic pulmonary inflammation.
β-Carotene is a major source of retinol and therefore is of particular significance in CF.
The aim of this study was to investigate the effect of daily intake of red palm oil (RPO) containing high amounts of β-carotene on the antioxidant levels in CF patients.
Sixteen subjects were recruited and instructed to enrich their food with 2 to 3 tablespoons of RPO (~1.5 mg of β-carotene) daily over 8 weeks.
Carotenoids, retinol, and α-tocopherol were measured in plasma at baseline and after intervention.
In addition β-carotene, lycopene, α-tocopherol, and vitamin C were measured in buccal mucosa cells (BMC) to determine the influence of RPO on antioxidant tissue levels.
Eleven subjects completed the study properly.
Plasma β-carotene, retinol, and α-carotene of these patients increased, but plasma concentrations of other carotenoids and α-tocopherol as well as concentrations of β-carotene, lycopene, α-tocopherol, and vitamin C in BMC remained unchanged.
Since RPO on a daily basis did not show negative side effects the data suggest that RPO may be used to elevate plasma β-carotene in CF.
American Psychological Association (APA)
Sommerburg, Olaf& De Spirt, Silke& Mattern, Annett& Joachim, Cornelia& Langhans, Claus-Dieter& Nesaretnam, Kalanithi…[et al.]. 2015. Supplementation with Red Palm Oil Increases β-Carotene and Vitamin A Blood Levels in Patients with Cystic Fibrosis. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072591
Modern Language Association (MLA)
Sommerburg, Olaf…[et al.]. Supplementation with Red Palm Oil Increases β-Carotene and Vitamin A Blood Levels in Patients with Cystic Fibrosis. Mediators of Inflammation No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1072591
American Medical Association (AMA)
Sommerburg, Olaf& De Spirt, Silke& Mattern, Annett& Joachim, Cornelia& Langhans, Claus-Dieter& Nesaretnam, Kalanithi…[et al.]. Supplementation with Red Palm Oil Increases β-Carotene and Vitamin A Blood Levels in Patients with Cystic Fibrosis. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1072591
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1072591