Protective Actions of 17β-Estradiol and Progesterone on Oxidative Neuronal Injury Induced by Organometallic Compounds
Joint Authors
Ishida, Atsuhiko
Ishihara, Yasuhiro
Yamazaki, Takeshi
Takemoto, Takuya
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-01
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Steroid hormones synthesized in and secreted from peripheral endocrine glands pass through the blood-brain barrier and play a role in the central nervous system.
In addition, the brain possesses an inherent endocrine system and synthesizes steroid hormones known as neurosteroids.
Increasing evidence shows that neuroactive steroids protect the central nervous system from various harmful stimuli.
Reports show that the neuroprotective actions of steroid hormones attenuate oxidative stress.
In this review, we summarize the antioxidative effects of neuroactive steroids, especially 17β-estradiol and progesterone, on neuronal injury in the central nervous system under various pathological conditions, and then describe our recent findings concerning the neuroprotective actions of 17β-estradiol and progesterone on oxidative neuronal injury induced by organometallic compounds, tributyltin, and methylmercury.
American Psychological Association (APA)
Ishihara, Yasuhiro& Takemoto, Takuya& Ishida, Atsuhiko& Yamazaki, Takeshi. 2015. Protective Actions of 17β-Estradiol and Progesterone on Oxidative Neuronal Injury Induced by Organometallic Compounds. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1075594
Modern Language Association (MLA)
Ishihara, Yasuhiro…[et al.]. Protective Actions of 17β-Estradiol and Progesterone on Oxidative Neuronal Injury Induced by Organometallic Compounds. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1075594
American Medical Association (AMA)
Ishihara, Yasuhiro& Takemoto, Takuya& Ishida, Atsuhiko& Yamazaki, Takeshi. Protective Actions of 17β-Estradiol and Progesterone on Oxidative Neuronal Injury Induced by Organometallic Compounds. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1075594
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075594