Delusional Disorder over the Reproductive Life Span: The Potential Influence of Menopause on the Clinical Course
Joint Authors
Penadés, Rafael
Catalán, Rosa
Bernardo, Miquel
González-Rodríguez, Alexandre
Molina-Andreu, Oriol
Garriga, Marina
Pons, Alexandre
Source
Schizophrenia Research and Treatment
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background and Objectives.
Recent evidence supports an association between estrogen levels and severity of psychopathology in schizophrenia women.
Our main goal was to investigate whether delusional disorder (DD) women with premenopausal onset and those with postmenopausal onset differ in demographic and clinical features.
Methods.
Psychopathological symptoms were assessed in 80 DD women (DSM-IV-TR), at baseline and after six and 24 months.
Scores in the PANSS, PSP for functionality, HRSD 17 items, C-SSRS for suicide, and the SUMD were considered outcome variables.
For comparison purposes, t- and χ2-tests were performed and nonparametric tests when necessary.
Analysis of Covariance (ANCOVA) was conducted for multivariate comparisons.
Results.
57 out of 80 DD women completed the study.
When unadjusted, DD with premenopausal onset had a longer DUP, higher educational level, and a tendency toward higher rates of gynaecological disorders.
Erotomanic type was most frequent in DD women premenopausal onset, and somatic and jealous types were most frequent in those with postmenopausal onset.
After 24 months, DD women with premenopausal onset showed higher depressive symptoms and a tendency toward higher rates of psychotic relapses.
Conclusions.
Our results support that some aspects of psychopathology and insight may differ according to the onset of DD and the reproductive status.
American Psychological Association (APA)
González-Rodríguez, Alexandre& Molina-Andreu, Oriol& Penadés, Rafael& Garriga, Marina& Pons, Alexandre& Catalán, Rosa…[et al.]. 2015. Delusional Disorder over the Reproductive Life Span: The Potential Influence of Menopause on the Clinical Course. Schizophrenia Research and Treatment،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1076119
Modern Language Association (MLA)
González-Rodríguez, Alexandre…[et al.]. Delusional Disorder over the Reproductive Life Span: The Potential Influence of Menopause on the Clinical Course. Schizophrenia Research and Treatment No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1076119
American Medical Association (AMA)
González-Rodríguez, Alexandre& Molina-Andreu, Oriol& Penadés, Rafael& Garriga, Marina& Pons, Alexandre& Catalán, Rosa…[et al.]. Delusional Disorder over the Reproductive Life Span: The Potential Influence of Menopause on the Clinical Course. Schizophrenia Research and Treatment. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1076119
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076119