Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering
Joint Authors
Li, Yuting
Meng, Hao
Liu, Yuan
Lee, Bruce P.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-17
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Due to the increasing needs for organ transplantation and a universal shortage of donated tissues, tissue engineering emerges as a useful approach to engineer functional tissues.
Although different synthetic materials have been used to fabricate tissue engineering scaffolds, they have many limitations such as the biocompatibility concerns, the inability to support cell attachment, and undesirable degradation rate.
Fibrin gel, a biopolymeric material, provides numerous advantages over synthetic materials in functioning as a tissue engineering scaffold and a cell carrier.
Fibrin gel exhibits excellent biocompatibility, promotes cell attachment, and can degrade in a controllable manner.
Additionally, fibrin gel mimics the natural blood-clotting process and self-assembles into a polymer network.
The ability for fibrin to cure in situ has been exploited to develop injectable scaffolds for the repair of damaged cardiac and cartilage tissues.
Additionally, fibrin gel has been utilized as a cell carrier to protect cells from the forces during the application and cell delivery processes while enhancing the cell viability and tissue regeneration.
Here, we review the recent advancement in developing fibrin-based biomaterials for the development of injectable tissue engineering scaffold and cell carriers.
American Psychological Association (APA)
Li, Yuting& Meng, Hao& Liu, Yuan& Lee, Bruce P.. 2015. Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1078979
Modern Language Association (MLA)
Li, Yuting…[et al.]. Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering. The Scientific World Journal No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1078979
American Medical Association (AMA)
Li, Yuting& Meng, Hao& Liu, Yuan& Lee, Bruce P.. Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1078979
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1078979