Experimental Forelimb Allotransplantation in Canine Model
Joint Authors
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
As reconstructive transplantation is gaining popularity as a viable alternative for upper limb amputees, it is becoming increasingly important for plastic surgeons to renew surgical skills and knowledge of this area.
Forelimb allotransplantation research has been performed previously in rodent and swine models.
However, preclinical canine forelimb allotransplantation studies are lacking in the literature.
The purpose of this paper is to provide an overview of the surgical skills necessary to successfully perform forelimb transplantation in canines as a means to prepare for clinical application.
A total of 18 transplantation operations on canines were performed.
The recipient limb was shortened at the one-third proximal forearm level.
The operation was performed in the following order: bones (two reconstructive plates), muscles and tendons (separately sutured), nerves (median, ulnar, and radial nerve), arteries (two), and veins (two).
The total mean time of transplantation was 5 hours ± 30 minutes.
All of the animals that received transplantation were treated with FK-506 (tacrolimus, 2 mg/kg) for 7 days after surgery.
Most allografts survived with perfect viability without vascular problems during the early postoperative period.
The canine forelimb allotransplantation model is well qualified to be a suitable training model for standard transplantation and future research work.
American Psychological Association (APA)
Hong, Sa-Hyeok& Eun, Seok-Chan. 2016. Experimental Forelimb Allotransplantation in Canine Model. BioMed Research International،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1096901
Modern Language Association (MLA)
Hong, Sa-Hyeok& Eun, Seok-Chan. Experimental Forelimb Allotransplantation in Canine Model. BioMed Research International No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1096901
American Medical Association (AMA)
Hong, Sa-Hyeok& Eun, Seok-Chan. Experimental Forelimb Allotransplantation in Canine Model. BioMed Research International. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1096901
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096901